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- W1989018416 abstract "We review the recent literature concerning the efficiency of antimicrobial photodynamic inactivation toward various microbial species in planktonic and biofilm cultures. The review is mainly focused on biofilm-growing microrganisms because this form of growth poses a threat to chronically infected or immunocompromised patients and is difficult to eradicate from medical devices. We discuss the biofilm formation process and mechanisms of its increased resistance to various antimicrobials. We present, based on data in the literature, strategies for overcoming the problem of biofilm resistance. Factors that have potential for use in increasing the efficiency of the killing of biofilm-forming bacteria include plant extracts, enzymes that disturb the biofilm structure, and other nonenzymatic molecules. We propose combining antimicrobial photodynamic therapy with various antimicrobial and antibiofilm approaches to obtain a synergistic effect to permit efficient microbial growth control at low photosensitizer doses." @default.
- W1989018416 created "2016-06-24" @default.
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- W1989018416 creator A5054715340 @default.
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- W1989018416 creator A5072027440 @default.
- W1989018416 date "2013-01-01" @default.
- W1989018416 modified "2023-10-16" @default.
- W1989018416 title "Innovative Strategies to Overcome Biofilm Resistance" @default.
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