Matches in SemOpenAlex for { <https://semopenalex.org/work/W1989043732> ?p ?o ?g. }
- W1989043732 endingPage "296" @default.
- W1989043732 startingPage "288" @default.
- W1989043732 abstract "Mitogen-activated protein kinases (MAPKs) are evolutionarily conserved enzymes in cell signal transduction. Previous studies revealed that zinc finger proteins are involved in the regulation of the MAPK signaling pathways. Here we report the identification and characterization of a novel human zinc finger protein, ZNF540. The cDNA of ZNF540 is 3.3kb, encoding 660 amino acids in the nucleus and the cytoplasm. Northern blot analysis indicates that ZNF540 is expressed in most of the fetal tissues. Overexpression of FLAG-ZNF540 in COS-7 cells represses the transcriptional activities of SRE and ELK-1, which can be relieved by siRNA. MVP, one of MAPK scaffold proteins, is identified as a potential ZNF540-binding protein. This interaction is detected by a yeast two-hybrid assay, reporter gene assays, and co-immunoprecipitation. Taken together, these results suggest that ZNF540 may act as a transcriptional repressor in MAPK signaling pathway to mediate cellular functions." @default.
- W1989043732 created "2016-06-24" @default.
- W1989043732 creator A5006657706 @default.
- W1989043732 creator A5014149946 @default.
- W1989043732 creator A5021449466 @default.
- W1989043732 creator A5025976400 @default.
- W1989043732 creator A5044342317 @default.
- W1989043732 creator A5044922023 @default.
- W1989043732 creator A5048491053 @default.
- W1989043732 creator A5053704104 @default.
- W1989043732 creator A5054859377 @default.
- W1989043732 creator A5065813586 @default.
- W1989043732 creator A5089530056 @default.
- W1989043732 creator A5090134632 @default.
- W1989043732 date "2006-08-01" @default.
- W1989043732 modified "2023-09-24" @default.
- W1989043732 title "A novel human zinc finger protein ZNF540 interacts with MVP and inhibits transcriptional activities of the ERK signal pathway" @default.
- W1989043732 cites W1228798347 @default.
- W1989043732 cites W1494401713 @default.
- W1989043732 cites W1973912514 @default.
- W1989043732 cites W1990158689 @default.
- W1989043732 cites W1997685333 @default.
- W1989043732 cites W2003678246 @default.
- W1989043732 cites W2010791130 @default.
- W1989043732 cites W2014188686 @default.
- W1989043732 cites W2014364643 @default.
- W1989043732 cites W2014392572 @default.
- W1989043732 cites W2024330610 @default.
- W1989043732 cites W2032205265 @default.
- W1989043732 cites W2034522546 @default.
- W1989043732 cites W2044112363 @default.
- W1989043732 cites W2052808935 @default.
- W1989043732 cites W2059432019 @default.
- W1989043732 cites W2078057618 @default.
- W1989043732 cites W2081924229 @default.
- W1989043732 cites W2084913730 @default.
- W1989043732 cites W2089126365 @default.
- W1989043732 cites W2094049721 @default.
- W1989043732 cites W2106109160 @default.
- W1989043732 cites W2108048093 @default.
- W1989043732 cites W2111224981 @default.
- W1989043732 cites W2121668326 @default.
- W1989043732 cites W2122057254 @default.
- W1989043732 cites W2127230663 @default.
- W1989043732 cites W2133383018 @default.
- W1989043732 cites W2166871205 @default.
- W1989043732 cites W2179700842 @default.
- W1989043732 cites W50972535 @default.
- W1989043732 cites W95405051 @default.
- W1989043732 doi "https://doi.org/10.1016/j.bbrc.2006.06.076" @default.
- W1989043732 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16815308" @default.
- W1989043732 hasPublicationYear "2006" @default.
- W1989043732 type Work @default.
- W1989043732 sameAs 1989043732 @default.
- W1989043732 citedByCount "24" @default.
- W1989043732 countsByYear W19890437322012 @default.
- W1989043732 countsByYear W19890437322013 @default.
- W1989043732 countsByYear W19890437322014 @default.
- W1989043732 countsByYear W19890437322015 @default.
- W1989043732 countsByYear W19890437322016 @default.
- W1989043732 countsByYear W19890437322017 @default.
- W1989043732 countsByYear W19890437322018 @default.
- W1989043732 countsByYear W19890437322019 @default.
- W1989043732 countsByYear W19890437322020 @default.
- W1989043732 countsByYear W19890437322022 @default.
- W1989043732 countsByYear W19890437322023 @default.
- W1989043732 crossrefType "journal-article" @default.
- W1989043732 hasAuthorship W1989043732A5006657706 @default.
- W1989043732 hasAuthorship W1989043732A5014149946 @default.
- W1989043732 hasAuthorship W1989043732A5021449466 @default.
- W1989043732 hasAuthorship W1989043732A5025976400 @default.
- W1989043732 hasAuthorship W1989043732A5044342317 @default.
- W1989043732 hasAuthorship W1989043732A5044922023 @default.
- W1989043732 hasAuthorship W1989043732A5048491053 @default.
- W1989043732 hasAuthorship W1989043732A5053704104 @default.
- W1989043732 hasAuthorship W1989043732A5054859377 @default.
- W1989043732 hasAuthorship W1989043732A5065813586 @default.
- W1989043732 hasAuthorship W1989043732A5089530056 @default.
- W1989043732 hasAuthorship W1989043732A5090134632 @default.
- W1989043732 hasConcept C104317684 @default.
- W1989043732 hasConcept C153911025 @default.
- W1989043732 hasConcept C158448853 @default.
- W1989043732 hasConcept C184235292 @default.
- W1989043732 hasConcept C187882448 @default.
- W1989043732 hasConcept C190062978 @default.
- W1989043732 hasConcept C24284526 @default.
- W1989043732 hasConcept C53645450 @default.
- W1989043732 hasConcept C55493867 @default.
- W1989043732 hasConcept C57074206 @default.
- W1989043732 hasConcept C62478195 @default.
- W1989043732 hasConcept C71829478 @default.
- W1989043732 hasConcept C86339819 @default.
- W1989043732 hasConcept C86803240 @default.
- W1989043732 hasConcept C95444343 @default.
- W1989043732 hasConceptScore W1989043732C104317684 @default.
- W1989043732 hasConceptScore W1989043732C153911025 @default.
- W1989043732 hasConceptScore W1989043732C158448853 @default.
- W1989043732 hasConceptScore W1989043732C184235292 @default.