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- W1989052011 abstract "Progress along the path of the sodium pump cycle requires a stepwise recruitment of additional subunits for maximal activity. These results show that whereas a particle the size of the alpha beta protomer presents Na+,K+-ATPase activity at 10 microM ATP, an additional subunit, perhaps a second alpha-chain, is required to obtain the much greater Na+,K+-ATPase activity resulting from the occupation of low-affinity ATP sites at physiological ATP concentrations. A non-phosphorylating ATP analogue, however, will modestly stimulate the Na+,K+-ATPase activity acting at an alternative low-affinity site or step on the alpha beta protomer." @default.
- W1989052011 created "2016-06-24" @default.
- W1989052011 creator A5002228204 @default.
- W1989052011 date "1987-12-10" @default.
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- W1989052011 title "The molecular size required varies according to the reaction step round the sodium pump cycle" @default.
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- W1989052011 doi "https://doi.org/10.1016/0014-5793(87)81147-x" @default.
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