Matches in SemOpenAlex for { <https://semopenalex.org/work/W1989078451> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W1989078451 endingPage "800" @default.
- W1989078451 startingPage "800" @default.
- W1989078451 abstract "INTRODUCTION AND OBJECTIVE: In the pre-planned analysis of the REDUCE study, the incidence of biopsy-detectable prostate cancer (PCa) is summarized using several methods, which yield different observed rates of PCa incidence. METHODS: REDUCE is an ongoing 4-year, international, randomized, double-blind, placebo-controlled, parallel-group study investigating the efficacy of dutasteride in reducing the risk of biopsydetectable prostate cancer. Eligible subjects were aged 5075 years, with a serum prostate specific antigen (PSA) 2.5-10 ng/mL (men aged 50-60 years) or 3.0-10 ng/mL (men aged >60 years) and a single, negative biopsy of 6-12 cores within 6 months prior to enrollment. After 2 and 4 years of treatment, transrectal ultrasound directed biopsies (10 cores) were performed. Blinded 2-year PCa results for all subjects are available and are summarized using crude, restricted crude, and modified crude rate methods. RESULTS: Definitions for each of the 3 methods for calculation of prostate cancer incidence are listed in the table below along with the actual calculated blinded 2-year results for subjects in the efficacy population (subjects with no PCa in baseline biopsy as assessed by the central pathology lab and who took at least one dose of study medication; n=8108). Blinded 2-year PCa rates in REDUCE" @default.
- W1989078451 created "2016-06-24" @default.
- W1989078451 creator A5025398154 @default.
- W1989078451 creator A5033438553 @default.
- W1989078451 creator A5046102633 @default.
- W1989078451 creator A5068197546 @default.
- W1989078451 creator A5086081364 @default.
- W1989078451 date "2009-04-01" @default.
- W1989078451 modified "2023-10-17" @default.
- W1989078451 title "INCIDENCE OF BIOPSY-DETECTABLE PROSTATE CANCER IN THE REDUCTION BY DUTASTERIDE OF PROSTATE CANCER EVENTS (REDUCE) TRIAL: BLINDED 2-YEAR RESULTS" @default.
- W1989078451 doi "https://doi.org/10.1016/s0022-5347(09)62229-1" @default.
- W1989078451 hasPublicationYear "2009" @default.
- W1989078451 type Work @default.
- W1989078451 sameAs 1989078451 @default.
- W1989078451 citedByCount "2" @default.
- W1989078451 crossrefType "journal-article" @default.
- W1989078451 hasAuthorship W1989078451A5025398154 @default.
- W1989078451 hasAuthorship W1989078451A5033438553 @default.
- W1989078451 hasAuthorship W1989078451A5046102633 @default.
- W1989078451 hasAuthorship W1989078451A5068197546 @default.
- W1989078451 hasAuthorship W1989078451A5086081364 @default.
- W1989078451 hasConcept C120665830 @default.
- W1989078451 hasConcept C121332964 @default.
- W1989078451 hasConcept C121608353 @default.
- W1989078451 hasConcept C126322002 @default.
- W1989078451 hasConcept C126894567 @default.
- W1989078451 hasConcept C143998085 @default.
- W1989078451 hasConcept C2775934546 @default.
- W1989078451 hasConcept C2776235491 @default.
- W1989078451 hasConcept C2778878792 @default.
- W1989078451 hasConcept C2780192828 @default.
- W1989078451 hasConcept C2781217009 @default.
- W1989078451 hasConcept C61511704 @default.
- W1989078451 hasConcept C71924100 @default.
- W1989078451 hasConceptScore W1989078451C120665830 @default.
- W1989078451 hasConceptScore W1989078451C121332964 @default.
- W1989078451 hasConceptScore W1989078451C121608353 @default.
- W1989078451 hasConceptScore W1989078451C126322002 @default.
- W1989078451 hasConceptScore W1989078451C126894567 @default.
- W1989078451 hasConceptScore W1989078451C143998085 @default.
- W1989078451 hasConceptScore W1989078451C2775934546 @default.
- W1989078451 hasConceptScore W1989078451C2776235491 @default.
- W1989078451 hasConceptScore W1989078451C2778878792 @default.
- W1989078451 hasConceptScore W1989078451C2780192828 @default.
- W1989078451 hasConceptScore W1989078451C2781217009 @default.
- W1989078451 hasConceptScore W1989078451C61511704 @default.
- W1989078451 hasConceptScore W1989078451C71924100 @default.
- W1989078451 hasIssue "4S" @default.
- W1989078451 hasLocation W19890784511 @default.
- W1989078451 hasOpenAccess W1989078451 @default.
- W1989078451 hasPrimaryLocation W19890784511 @default.
- W1989078451 hasRelatedWork W1725314107 @default.
- W1989078451 hasRelatedWork W1748509901 @default.
- W1989078451 hasRelatedWork W2041562209 @default.
- W1989078451 hasRelatedWork W2047986592 @default.
- W1989078451 hasRelatedWork W2099948048 @default.
- W1989078451 hasRelatedWork W2102167265 @default.
- W1989078451 hasRelatedWork W2110860120 @default.
- W1989078451 hasRelatedWork W2336014336 @default.
- W1989078451 hasRelatedWork W2606218154 @default.
- W1989078451 hasRelatedWork W3163649103 @default.
- W1989078451 hasVolume "181" @default.
- W1989078451 isParatext "false" @default.
- W1989078451 isRetracted "false" @default.
- W1989078451 magId "1989078451" @default.
- W1989078451 workType "article" @default.