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• W1989181769 abstract "Chemical investigation of the tunicate Trididemnum solidum resulted in the isolation of two new chlorinated compounds belonging to the didemnin class, along with two known compounds didemnin A and didemnin B. The structural determination of the compounds was based on extensive NMR and mass spectroscopic analysis. The isolated compounds 1-4 were tested for their anti-inflammatory activity using in vitro assays for inhibition of inducible nitric oxide synthase (iNOS) and nuclear factor-kappa B (NF-κB) activity. The anti-cell proliferative activity of the above compounds was also evaluated against four solid tumor cell lines." @default.
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• W1989181769 date "2013-11-11" @default.
• W1989181769 modified "2023-10-14" @default.
• W1989181769 title "Chlorinated Didemnins from the Tunicate Trididemnum solidum" @default.
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• W1989181769 doi "https://doi.org/10.3390/md11114478" @default.
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