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• W1989279736 abstract "No AccessJournal of UrologyAdult Urology1 Nov 2008Predicting Differential Renal Function Using Computerized Tomography Measurements of Renal Parenchymal Areais accompanied byPredicting Irreparable Renal Ischemic Injury Using a Real-Time Marker in the Porcine Model Marc T. Feder, Jeffery Blitstein, Barry Mason, and David M. Hoenig Marc T. FederMarc T. Feder More articles by this author , Jeffery BlitsteinJeffery Blitstein More articles by this author , Barry MasonBarry Mason More articles by this author , and David M. HoenigDavid M. Hoenig Financial interest and/or other relationship with Boston Scientific, Applied Medical and Cryolife. More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2008.07.057AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We evaluated any correlation between measured renal parenchymal area on computerized tomography and differential function on 99mtechnetium-mercaptoacetyltriglycine renal scan to ascertain whether computerized tomography measurements could predict differential renal function. Materials and Methods: Between 2005 and 2007 we identified 111 patients who underwent computerized tomography and renal scan. Average renal parenchymal thickness was calculated by measurements made at the upper and lower poles of each kidney. The product of average renal parenchymal thickness and renal length was calculated bilaterally and the ratio of parenchymal area was compared to the differential shown on renal scan. Results: The average difference between predicted and observed renal function was 4.73% (Pearson's correlation coefficient 0.959). Patients with positive urine cultures at renal scan were compared to the other 89. The average functional difference was 6.54% vs 4.28% (Pearson's correlation 0.955 vs 0.965, p = 0.0045). The 89 uninfected patients were then compared based on contrast vs noncontrast computerized tomography and obstructed vs unobstructed renal units. No statistical difference was found with contrast administration. When compared based on evidence of obstruction, unobstructed kidneys resulted in a lower Pearson correlation (0.743 vs 0.975) but they had a statistically significant average functional difference in favor of unobstructed units (3.28% vs 5.10%, p = 0.0036). No difference was found in the obstructed group with prior drain placement. Conclusions: Differential renal parenchymal area measured by computerized tomography strongly correlates with differential function on renal scintigraphy and it may obviate the need for nuclear renal scan in some circumstances. References 1 : Radionuclide imaging in urology. Urol Clin North Am2006; 33: 319. Google Scholar 2 : Pathophysiology of urinary tract obstruction. In: Campbell-Walsh Urology. Edited by . Philadelphia: WB Saunders2007: 1195. Google Scholar 3 : Cortical thickness: an early morphological marker of atherosclerotic renal disease. Kidney Int2002; 61: 591. Google Scholar 4 : Prediction of differential creatinine clearance in chronically obstructed kidneys by non-contrast helical computerized tomography. Int Braz J Urol2004; 30: 102. Google Scholar 5 : The correlation between ultrasound-detected renal parenchymal thickness and isotope detected individual renal function. Kaohsiung J Med Sci1997; 13: 682. Google Scholar Department of Urology, Albert Einstein College of Medicine-Montefiore Medical Center, Bronx, New York© 2008 by American Urological AssociationFiguresReferencesRelatedDetailsRelated articlesJournal of Urology22 Sep 2008Predicting Irreparable Renal Ischemic Injury Using a Real-Time Marker in the Porcine Model Volume 180Issue 5November 2008Page: 2110-2115 Advertisement Copyright & Permissions© 2008 by American Urological AssociationKeywordskidney function testsorgan sizekidneytomography, emission-computedradionuclide imagingMetricsAuthor Information Marc T. Feder More articles by this author Jeffery Blitstein More articles by this author Barry Mason More articles by this author David M. Hoenig Financial interest and/or other relationship with Boston Scientific, Applied Medical and Cryolife. More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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• W1989279736 title "Predicting Differential Renal Function Using Computerized Tomography Measurements of Renal Parenchymal Area" @default.
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