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- W1989291244 abstract "Nutritional factors, such as an excess or a deficiency of glucose, play an important role in neuroendocrine regulations. Hormonal and metabolic responses to hypoglycemia were examined in healthy non-obese volunteers under conditions of low ambient temperature. Hypoglycemia was induced by intravenous injection of insulin in two randomized trials performed at room temperature and at 4°C. At room temperature, the typical neuroendocrine response to hypoglycemia was established. The increases of ACTH, β-endorphin, growth hormone and Cortisol in response to insulin hypoglycemia failed to be modified by low ambient temperature. Acute cold exposure significantly reduced epinephrine and totally inhibited prolactin response to insulin-induced hypoglycemia. In spite of significant changes in epinephrine response to hypoglycemia at low ambient temperature, no striking differences in plasma glucose levels compared to those measured at room temperature were observed. However, under conditions of low temperature the reestablishment of normoglycemia was delayed. No changes in free fatty acids were found under our experimental conditions. The presented data show that low ambient temperature exerts selective effects on some neuroendocrine and metabolic parameters." @default.
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- W1989291244 date "1995-12-01" @default.
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- W1989291244 title "Low Ambient Temperature and Neuroendocrine Response to Hypoglycemia in Men" @default.
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- W1989291244 doi "https://doi.org/10.1002/j.1550-8528.1995.tb00490.x" @default.
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