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- W1989292079 abstract "Catecholestrogens and especially 2-hydroxyestrone (2OH-E1) are estradiol metabolites locally formed in breast cancer cells. The present study demonstrates that the two parent compounds, estradiol (E2) and its metabolite 2OH-E1, exert opposite effects on hormone-sensitive breast cancer cell growth assessed by cell counts and transferrin receptor levels, and also on cell differentiation assessed by secreted proteins such as alpha-lactalbumin and gross cystic disease fluid protein (GCDFP-15). The present findings may highlight estradiol regulation in hormone-sensitive breast cancer cells." @default.
- W1989292079 created "2016-06-24" @default.
- W1989292079 creator A5042269235 @default.
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- W1989292079 date "1989-02-01" @default.
- W1989292079 modified "2023-09-24" @default.
- W1989292079 title "Opposite effects of estrogen and catecholestrogen on hormone-sensitive breast cancer cell growth and differentiation" @default.
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- W1989292079 doi "https://doi.org/10.1016/0303-7207(89)90135-4" @default.
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