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• W1989297922 endingPage "48" @default.
• W1989297922 startingPage "37" @default.
• W1989297922 abstract "Depression, anxiety, or both, during pregnancy are common complications during the perinatal period, with 15-20% of women experiencing depression at some point during their pregnancy. Considerable evidence suggests that untreated or undertreated maternal Axis I mood disorders can increase the risk for preterm birth, low birth weight, and alter neurobehavioral development in utero. Serotonin reuptake inhibitor antidepressants are often considered for antenatal therapy, with the goal of improving maternal mental health during pregnancy. Treatment with a serotonin-reuptake inhibitor, however, does not guarantee remission of depression, and in-utero serotonin reuptake inhibitor exposure has also been linked to increased risks for adverse infant outcomes. In this chapter, evidence linking serotonin reuptake inhibitor use with an increased risk for postnatal adaptation syndrome, congenital heart defects, and neonatal persistent pulmonary hypertension is reviewed. Management decisions should include attention to the continuum of depression symptoms, from subclinical to severe major depressive disorder and the long-term developmental risks that might also be associated with pre- and postnatal exposure." @default.
• W1989297922 created "2016-06-24" @default.
• W1989297922 creator A5026941564 @default.
• W1989297922 creator A5028020809 @default.
• W1989297922 date "2014-01-01" @default.
• W1989297922 modified "2023-10-06" @default.
• W1989297922 title "The effect of perinatal exposures on the infant: Antidepressants and depression" @default.
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