Matches in SemOpenAlex for { <https://semopenalex.org/work/W1989299874> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1989299874 endingPage "240" @default.
- W1989299874 startingPage "225" @default.
- W1989299874 abstract "αBT is a snake toxin which in vertebrate systems binds with great specificity to ACh receptors. We have studied the effects of αBT on the electrophysiological response to ACh of identifiable cells in the nervous system of the marine mollusc, Aplysia, and the binding of [125I]αBT to a ganglionic preparation. Aplysia has 3 pharmacologically distinct ACh responses and each causes a different conductance change. αBT blocks all 3 responses of iontophoretically applied ACh. In all cases the inhibition is reversed on washing. Binding of [125I]αBT to the ganglionic preparation is a saturable process. The dissociation constant of binding calculated from rates of association and dissociation of the toxin-receptor complex is0.8 × 10−9 M. Binding of [125I]αBT is inhibited by unlabeled toxin, ACh agonists, and antagonists as well as by eserine, ouabain, and TEA but not by the transmitters serotonin and dopamine." @default.
- W1989299874 created "2016-06-24" @default.
- W1989299874 creator A5016718098 @default.
- W1989299874 creator A5050331720 @default.
- W1989299874 creator A5070504998 @default.
- W1989299874 creator A5074232978 @default.
- W1989299874 creator A5086879348 @default.
- W1989299874 date "1974-06-01" @default.
- W1989299874 modified "2023-10-14" @default.
- W1989299874 title "Aplysia acetylcholine receptors: Blockade by and binding of α-bungarotoxin" @default.
- W1989299874 cites W1525268213 @default.
- W1989299874 cites W1775749144 @default.
- W1989299874 cites W1910258660 @default.
- W1989299874 cites W1970580564 @default.
- W1989299874 cites W1972293076 @default.
- W1989299874 cites W1977610876 @default.
- W1989299874 cites W1982218403 @default.
- W1989299874 cites W2001766383 @default.
- W1989299874 cites W2006090981 @default.
- W1989299874 cites W2007777365 @default.
- W1989299874 cites W2019627679 @default.
- W1989299874 cites W2023707571 @default.
- W1989299874 cites W2034684185 @default.
- W1989299874 cites W2037251446 @default.
- W1989299874 cites W2053413143 @default.
- W1989299874 cites W2055889678 @default.
- W1989299874 cites W2060929764 @default.
- W1989299874 cites W2063042968 @default.
- W1989299874 cites W2064631662 @default.
- W1989299874 cites W2073166579 @default.
- W1989299874 cites W2078721905 @default.
- W1989299874 cites W2095082106 @default.
- W1989299874 cites W2131397357 @default.
- W1989299874 cites W2134218003 @default.
- W1989299874 cites W2176498237 @default.
- W1989299874 cites W2340255892 @default.
- W1989299874 cites W2460220573 @default.
- W1989299874 cites W93629758 @default.
- W1989299874 doi "https://doi.org/10.1016/0006-8993(74)90861-0" @default.
- W1989299874 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4151724" @default.
- W1989299874 hasPublicationYear "1974" @default.
- W1989299874 type Work @default.
- W1989299874 sameAs 1989299874 @default.
- W1989299874 citedByCount "57" @default.
- W1989299874 crossrefType "journal-article" @default.
- W1989299874 hasAuthorship W1989299874A5016718098 @default.
- W1989299874 hasAuthorship W1989299874A5050331720 @default.
- W1989299874 hasAuthorship W1989299874A5070504998 @default.
- W1989299874 hasAuthorship W1989299874A5074232978 @default.
- W1989299874 hasAuthorship W1989299874A5086879348 @default.
- W1989299874 hasConcept C12554922 @default.
- W1989299874 hasConcept C169760540 @default.
- W1989299874 hasConcept C170493617 @default.
- W1989299874 hasConcept C185592680 @default.
- W1989299874 hasConcept C2775864247 @default.
- W1989299874 hasConcept C2775910092 @default.
- W1989299874 hasConcept C2777186327 @default.
- W1989299874 hasConcept C2778178740 @default.
- W1989299874 hasConcept C55493867 @default.
- W1989299874 hasConcept C74998103 @default.
- W1989299874 hasConcept C80161118 @default.
- W1989299874 hasConcept C86803240 @default.
- W1989299874 hasConcept C98274493 @default.
- W1989299874 hasConceptScore W1989299874C12554922 @default.
- W1989299874 hasConceptScore W1989299874C169760540 @default.
- W1989299874 hasConceptScore W1989299874C170493617 @default.
- W1989299874 hasConceptScore W1989299874C185592680 @default.
- W1989299874 hasConceptScore W1989299874C2775864247 @default.
- W1989299874 hasConceptScore W1989299874C2775910092 @default.
- W1989299874 hasConceptScore W1989299874C2777186327 @default.
- W1989299874 hasConceptScore W1989299874C2778178740 @default.
- W1989299874 hasConceptScore W1989299874C55493867 @default.
- W1989299874 hasConceptScore W1989299874C74998103 @default.
- W1989299874 hasConceptScore W1989299874C80161118 @default.
- W1989299874 hasConceptScore W1989299874C86803240 @default.
- W1989299874 hasConceptScore W1989299874C98274493 @default.
- W1989299874 hasIssue "2" @default.
- W1989299874 hasLocation W19892998741 @default.
- W1989299874 hasLocation W19892998742 @default.
- W1989299874 hasOpenAccess W1989299874 @default.
- W1989299874 hasPrimaryLocation W19892998741 @default.
- W1989299874 hasRelatedWork W1795842104 @default.
- W1989299874 hasRelatedWork W1915000884 @default.
- W1989299874 hasRelatedWork W1987815847 @default.
- W1989299874 hasRelatedWork W1988615846 @default.
- W1989299874 hasRelatedWork W1989299874 @default.
- W1989299874 hasRelatedWork W1990648371 @default.
- W1989299874 hasRelatedWork W2037787290 @default.
- W1989299874 hasRelatedWork W2064124977 @default.
- W1989299874 hasRelatedWork W2133494168 @default.
- W1989299874 hasRelatedWork W2141284133 @default.
- W1989299874 hasVolume "72" @default.
- W1989299874 isParatext "false" @default.
- W1989299874 isRetracted "false" @default.
- W1989299874 magId "1989299874" @default.
- W1989299874 workType "article" @default.