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• W1989334420 abstract "The switch from vegetative to reproductive development in plants necessitates a switch in the developmental program of the descendents of the stem cells in the shoot apical meristem. Genetic and molecular investigations have demonstrated that the plant-specific transcription factor and meristem identity regulator LEAFY (LFY) controls this developmental transition by inducing expression of a second transcription factor, APETALA1, and by regulating the expression of additional, as yet unknown, genes. Here we show that the additional LFY targets include the APETALA1-related factor, CAULI-FLOWER, as well as three transcription factors and two putative signal transduction pathway components. These genes are up-regulated by LFY even when protein synthesis is inhibited and, hence, appear to be direct targets of LFY. Supporting this conclusion, cis-regulatory regions upstream of these genes are bound by LFY in vivo . The newly identified LFY targets likely initiate the transcriptional changes that are required for the switch from vegetative to reproductive development in Arabidopsis ." @default.
• W1989334420 created "2016-06-24" @default.
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• W1989334420 date "2004-01-21" @default.
• W1989334420 modified "2023-10-01" @default.
• W1989334420 title "Genomic identification of direct target genes of LEAFY" @default.
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• W1989334420 doi "https://doi.org/10.1073/pnas.0307842100" @default.
• W1989334420 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/341852" @default.
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