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- W1989399037 abstract "Abstract Priming rats with the carrier protein 7 – 43 days before injecting them with a conjugate of hapten NIP [(4‐hydroxy‐5‐iodo‐3‐nitrophenyl)acetyl] and the protein accelerated the anti‐hapten response: peak titers were reached sooner, the replacement of IgM by IgG antibody happened earlier and the affinity of anti‐NIP was higher in carrier‐primed than in non‐carrier‐primed rats. The acceleration effect on peak titers was short‐lasting. By day 9 the anti‐hapten titers in non‐carrier‐primed animals had reached those of the carrier‐primed animals. The difference in affinities gradually decreased, but was still demonstrable 28 days after immunization with the conjugate." @default.
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- W1989399037 date "1973-04-01" @default.
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- W1989399037 title "Affinity and Ig classes of anti-hapten antibodies in carrier-preimmunized rats" @default.
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- W1989399037 doi "https://doi.org/10.1002/eji.1830030403" @default.
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