Matches in SemOpenAlex for { <https://semopenalex.org/work/W1989444656> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W1989444656 abstract "The selective toxicity of CB 1954 (5-aziridinyl-2,4-dinitrobenzamide) for Walker tumour cells, previously shown in the whole animal and in an in vitro/in vivo system, has been confirmed in an in vitro system In each case its actions on the Walker tumour were reversed by 4-amino-5-imidazolecarboxamide, the ribotide of which is a purine precursor, provided it was given before or soon after the CB 1954. Other purines also produced this reversal, while pyrimidines and several other compounds did not. This evidence suggested that CB 1954, in addition to its alkylating properties, had features of a purine antimetabolite. However, anthranilamide was also very effective in protecting against CB 1954, suggesting that reversal could be achieved by compounds structurally related to CB 1954 which competed with it for some receptor site." @default.
- W1989444656 created "2016-06-24" @default.
- W1989444656 creator A5016356476 @default.
- W1989444656 creator A5056997693 @default.
- W1989444656 creator A5076687895 @default.
- W1989444656 date "1972-01-15" @default.
- W1989444656 modified "2023-09-24" @default.
- W1989444656 title "Studies on the reversal of the selective antitumour effect of the aziridinyl derivative cb 1954 by 4-amino-5-imidazolecarboxamide" @default.
- W1989444656 cites W1997884805 @default.
- W1989444656 cites W2002753229 @default.
- W1989444656 cites W2036983895 @default.
- W1989444656 cites W2048010533 @default.
- W1989444656 cites W2323394770 @default.
- W1989444656 doi "https://doi.org/10.1002/ijc.2910090115" @default.
- W1989444656 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5015661" @default.
- W1989444656 hasPublicationYear "1972" @default.
- W1989444656 type Work @default.
- W1989444656 sameAs 1989444656 @default.
- W1989444656 citedByCount "23" @default.
- W1989444656 crossrefType "journal-article" @default.
- W1989444656 hasAuthorship W1989444656A5016356476 @default.
- W1989444656 hasAuthorship W1989444656A5056997693 @default.
- W1989444656 hasAuthorship W1989444656A5076687895 @default.
- W1989444656 hasConcept C104317684 @default.
- W1989444656 hasConcept C109246011 @default.
- W1989444656 hasConcept C169586020 @default.
- W1989444656 hasConcept C178790620 @default.
- W1989444656 hasConcept C181199279 @default.
- W1989444656 hasConcept C185592680 @default.
- W1989444656 hasConcept C202751555 @default.
- W1989444656 hasConcept C207001950 @default.
- W1989444656 hasConcept C2776476023 @default.
- W1989444656 hasConcept C2776543447 @default.
- W1989444656 hasConcept C2778397455 @default.
- W1989444656 hasConcept C29730261 @default.
- W1989444656 hasConcept C512185932 @default.
- W1989444656 hasConcept C54355233 @default.
- W1989444656 hasConcept C55493867 @default.
- W1989444656 hasConcept C71240020 @default.
- W1989444656 hasConcept C86803240 @default.
- W1989444656 hasConcept C98892162 @default.
- W1989444656 hasConceptScore W1989444656C104317684 @default.
- W1989444656 hasConceptScore W1989444656C109246011 @default.
- W1989444656 hasConceptScore W1989444656C169586020 @default.
- W1989444656 hasConceptScore W1989444656C178790620 @default.
- W1989444656 hasConceptScore W1989444656C181199279 @default.
- W1989444656 hasConceptScore W1989444656C185592680 @default.
- W1989444656 hasConceptScore W1989444656C202751555 @default.
- W1989444656 hasConceptScore W1989444656C207001950 @default.
- W1989444656 hasConceptScore W1989444656C2776476023 @default.
- W1989444656 hasConceptScore W1989444656C2776543447 @default.
- W1989444656 hasConceptScore W1989444656C2778397455 @default.
- W1989444656 hasConceptScore W1989444656C29730261 @default.
- W1989444656 hasConceptScore W1989444656C512185932 @default.
- W1989444656 hasConceptScore W1989444656C54355233 @default.
- W1989444656 hasConceptScore W1989444656C55493867 @default.
- W1989444656 hasConceptScore W1989444656C71240020 @default.
- W1989444656 hasConceptScore W1989444656C86803240 @default.
- W1989444656 hasConceptScore W1989444656C98892162 @default.
- W1989444656 hasLocation W19894446561 @default.
- W1989444656 hasLocation W19894446562 @default.
- W1989444656 hasOpenAccess W1989444656 @default.
- W1989444656 hasPrimaryLocation W19894446561 @default.
- W1989444656 hasRelatedWork W1983655658 @default.
- W1989444656 hasRelatedWork W2026749510 @default.
- W1989444656 hasRelatedWork W2057539041 @default.
- W1989444656 hasRelatedWork W2068203377 @default.
- W1989444656 hasRelatedWork W2312909371 @default.
- W1989444656 hasRelatedWork W2322770650 @default.
- W1989444656 hasRelatedWork W2329407854 @default.
- W1989444656 hasRelatedWork W2952578443 @default.
- W1989444656 hasRelatedWork W2953238405 @default.
- W1989444656 hasRelatedWork W3005124540 @default.
- W1989444656 isParatext "false" @default.
- W1989444656 isRetracted "false" @default.
- W1989444656 magId "1989444656" @default.
- W1989444656 workType "article" @default.