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• W1989445638 endingPage "355" @default.
• W1989445638 startingPage "343" @default.
• W1989445638 abstract "Eukaryotic mRNA biogenesis involves a series of interconnected steps, including nuclear pre-mRNA processing, mRNA export, and surveillance. The exon-junction complex (EJC) is deposited on newly spliced mRNAs and coordinates several downstream steps of mRNA biogenesis. The EJC core protein, Y14, functions with its partners in nonsense-mediated mRNA decay and translational enhancement. Y14 plays additional roles in mRNA metabolism, some of which are independent of the EJC, and it is also involved in other cellular processes. Genetic mutations or aberrant expression of Y14 results in physiological abnormality and may cause disease. Therefore, it is important to understand the various functions of Y14 and its physiological and pathological roles." @default.
• W1989445638 created "2016-06-24" @default.
• W1989445638 creator A5004752410 @default.
• W1989445638 creator A5016980965 @default.
• W1989445638 creator A5046683580 @default.
• W1989445638 date "2015-04-10" @default.
• W1989445638 modified "2023-10-13" @default.
• W1989445638 title "Function and Pathological Implications of Exon Junction Complex Factor Y14" @default.
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