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- W1989479815 endingPage "228" @default.
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- W1989479815 abstract "Protected peptide fragments are valuable building blocks for the assembly of large peptide sequences through fragment condensation approaches, whereas protected peptides are typically synthesized for the preparation of amide-bridge cyclic peptides in solution. Efficient synthesis of both protected peptides and protected peptide fragments by solid-phase peptide synthesis methodology requires handles that attach the growing peptides to the polymeric support and can be cleaved under appropriate conditions, while maintaining intact the side-chain protecting groups. Here, we provide an overview of attachment methods described in the literature for the preparation of protected peptides using Fmoc/tBu chemistry, including the most commonly used acid-labile linkers along with the most recent and sophisticated." @default.
- W1989479815 created "2016-06-24" @default.
- W1989479815 creator A5013551382 @default.
- W1989479815 creator A5024381923 @default.
- W1989479815 creator A5068795619 @default.
- W1989479815 date "2013-04-26" @default.
- W1989479815 modified "2023-10-16" @default.
- W1989479815 title "Handles for Fmoc Solid-Phase Synthesis of Protected Peptides" @default.
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- W1989479815 doi "https://doi.org/10.1021/co300153c" @default.
- W1989479815 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23573835" @default.
- W1989479815 hasPublicationYear "2013" @default.
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