FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1989504562> ?p ?o ?g. }

• W1989504562 endingPage "439" @default.
• W1989504562 startingPage "431" @default.
• W1989504562 abstract "Based upon findings that the scatter factor/hepatocyte growth factor (SF/HGF) has strong mitogenic and motogenic properties, and that the sperm cell acquires its fertilizing capacity and motility in the distal parts of mammalian epididymis, the present study was conducted to investigate the role of SF/HGF in initiation of sperm cell motility. This was investigated by determining the expression of SF/HGF in various regions of the murine male genital tract by scatter and cell tracking assays using MDCK epithelial cells, Western blot procedure, and the immunohistochemical procedure using paraffin sections of various regions of the male genital tract. The findings from all these assays indicate that SF/HGF is differentially expressed in various parts of the male genital tract with slight or no expression in the testes, caput epididymis, and vas deferens, and with the highest expression in cauda and corpus (distal) epididymis followed by expression in the corpus (proximal) epididymis. This region-specific SF/HGF expression pattern coincides with the pattern of acquiring the fertilizing capacity and motility by the sperm cell during its transit through the male genital tract. However, wherever SF/HGF was expressed in the male genital tract, its molecular weight was slightly higher (Mr, 82 kD), compared to the SF/HGF expressed in various other somatic tissues (Mr, 78 kD), indicating that the genital tract SF/HGF may be a different molecular species that shares some immunoreactive epitopes with the somatic cell SF/HGF. Incubation of immotile sperm from caput epididymis with the purified human placental SF/HGF of 78 kD initiated motility in 5-15% of sperm population. These results strongly suggest that the SF/HGF-like activity is expressed in the male genital tract in a region-specific manner, and this activity may have a role in initiation of sperm motility acquired during its transit through the epididymis in mammals." @default.
• W1989504562 created "2016-06-24" @default.
• W1989504562 creator A5032262345 @default.
• W1989504562 creator A5036394500 @default.
• W1989504562 creator A5050154898 @default.
• W1989504562 creator A5055710749 @default.
• W1989504562 creator A5088337191 @default.
• W1989504562 date "1994-08-01" @default.
• W1989504562 modified "2023-09-27" @default.
• W1989504562 title "Expression of scatter factor/hepatocyte growth factor is regionally correlated with the initiation of sperm motility in murine male genital tract: Is scatter factor/hepatocyte growth factor involved in initiation of sperm motility?" @default.
• W1989504562 cites W117902596 @default.
• W1989504562 cites W144921617 @default.
• W1989504562 cites W1525300546 @default.
• W1989504562 cites W1793582010 @default.
• W1989504562 cites W1963794212 @default.
• W1989504562 cites W1979522094 @default.
• W1989504562 cites W2005782838 @default.
• W1989504562 cites W2032359283 @default.
• W1989504562 cites W2036550849 @default.
• W1989504562 cites W2054042846 @default.
• W1989504562 cites W2059530496 @default.
• W1989504562 cites W2078188783 @default.
• W1989504562 cites W2078753736 @default.
• W1989504562 cites W2081844653 @default.
• W1989504562 cites W2084751426 @default.
• W1989504562 cites W2100837269 @default.
• W1989504562 cites W2101108802 @default.
• W1989504562 cites W2128274330 @default.
• W1989504562 cites W2134491006 @default.
• W1989504562 cites W2135161383 @default.
• W1989504562 cites W2135958846 @default.
• W1989504562 cites W2153580778 @default.
• W1989504562 cites W2338662446 @default.
• W1989504562 cites W2430236159 @default.
• W1989504562 cites W4293247451 @default.
• W1989504562 doi "https://doi.org/10.1002/mrd.1080380411" @default.
• W1989504562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7980952" @default.
• W1989504562 hasPublicationYear "1994" @default.
• W1989504562 type Work @default.
• W1989504562 sameAs 1989504562 @default.
• W1989504562 citedByCount "21" @default.
• W1989504562 countsByYear W19895045622012 @default.
• W1989504562 countsByYear W19895045622014 @default.
• W1989504562 countsByYear W19895045622018 @default.
• W1989504562 countsByYear W19895045622021 @default.
• W1989504562 crossrefType "journal-article" @default.
• W1989504562 hasAuthorship W1989504562A5032262345 @default.
• W1989504562 hasAuthorship W1989504562A5036394500 @default.
• W1989504562 hasAuthorship W1989504562A5050154898 @default.
• W1989504562 hasAuthorship W1989504562A5055710749 @default.
• W1989504562 hasAuthorship W1989504562A5088337191 @default.
• W1989504562 hasConcept C104317684 @default.
• W1989504562 hasConcept C126322002 @default.
• W1989504562 hasConcept C134018914 @default.
• W1989504562 hasConcept C16685009 @default.
• W1989504562 hasConcept C170493617 @default.
• W1989504562 hasConcept C2776415932 @default.
• W1989504562 hasConcept C2776996007 @default.
• W1989504562 hasConcept C2777632594 @default.
• W1989504562 hasConcept C2778210472 @default.
• W1989504562 hasConcept C2781087480 @default.
• W1989504562 hasConcept C2781254305 @default.
• W1989504562 hasConcept C54355233 @default.
• W1989504562 hasConcept C58207958 @default.
• W1989504562 hasConcept C71924100 @default.
• W1989504562 hasConcept C86803240 @default.
• W1989504562 hasConcept C95444343 @default.
• W1989504562 hasConceptScore W1989504562C104317684 @default.
• W1989504562 hasConceptScore W1989504562C126322002 @default.
• W1989504562 hasConceptScore W1989504562C134018914 @default.
• W1989504562 hasConceptScore W1989504562C16685009 @default.
• W1989504562 hasConceptScore W1989504562C170493617 @default.
• W1989504562 hasConceptScore W1989504562C2776415932 @default.
• W1989504562 hasConceptScore W1989504562C2776996007 @default.
• W1989504562 hasConceptScore W1989504562C2777632594 @default.
• W1989504562 hasConceptScore W1989504562C2778210472 @default.
• W1989504562 hasConceptScore W1989504562C2781087480 @default.
• W1989504562 hasConceptScore W1989504562C2781254305 @default.
• W1989504562 hasConceptScore W1989504562C54355233 @default.
• W1989504562 hasConceptScore W1989504562C58207958 @default.
• W1989504562 hasConceptScore W1989504562C71924100 @default.
• W1989504562 hasConceptScore W1989504562C86803240 @default.
• W1989504562 hasConceptScore W1989504562C95444343 @default.
• W1989504562 hasIssue "4" @default.
• W1989504562 hasLocation W19895045621 @default.
• W1989504562 hasLocation W19895045622 @default.
• W1989504562 hasOpenAccess W1989504562 @default.
• W1989504562 hasPrimaryLocation W19895045621 @default.
• W1989504562 hasRelatedWork W1597978224 @default.
• W1989504562 hasRelatedWork W2053864443 @default.
• W1989504562 hasRelatedWork W2086560894 @default.
• W1989504562 hasRelatedWork W2390416156 @default.
• W1989504562 hasRelatedWork W2411215854 @default.
• W1989504562 hasRelatedWork W2540820835 @default.
• W1989504562 hasRelatedWork W2977270054 @default.
• W1989504562 hasRelatedWork W4214925635 @default.
• W1989504562 hasRelatedWork W4240074229 @default.
• W1989504562 hasRelatedWork W4381248989 @default.

• next