FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1989690681> ?p ?o ?g. }

• W1989690681 abstract "Corneal disease is responsible for the main cause of bilateral blindness in the world, second only to cataract. As an essential actin binding protein, destrin mutation often result in cytoskeleton dynamics abnormalities in corneal epithelial surface, and thus, cause corneal epithelial cell hyperproliferation, inflammation, and angiogenesis, namely, corneal diseases. In this study, we explored the interaction and crosstalk between pathways in response to destrin mutation. As we expected, the results showed that regulation of actin cytoskeleton was the significant pathway in destrin mutation mice. Further analysis indicated that there were 28 significant pathways crosstalk to pathway of regulation of actin cytoskeleton. Importantly, three pathways, including regulation of actin cytoskeleton pathway, pathway in cancer, and B cell receptor signaling pathway were linked by inositol phosphate metabolism in crosstalk analysis of GO relationships among pathways. All of them have been demonstrated to play important roles in cytoskeleton dynamics. We deeply hope that our study could provide insights into cytoskeleton dynamics abnormalities in destrin mutation corneal disease. Key words: ADF/cofilin, cytoskeleton dynamics, pathway crosstalk." @default.
• W1989690681 created "2016-06-24" @default.
• W1989690681 creator A5032020402 @default.
• W1989690681 creator A5047351745 @default.
• W1989690681 creator A5089470742 @default.
• W1989690681 date "2012-06-29" @default.
• W1989690681 modified "2023-09-26" @default.
• W1989690681 title "The effect of destrin mutations pathways on the gene expression profile" @default.
• W1989690681 cites W1538100539 @default.
• W1989690681 cites W1578104218 @default.
• W1989690681 cites W1967370640 @default.
• W1989690681 cites W1967518676 @default.
• W1989690681 cites W1981954655 @default.
• W1989690681 cites W1988258262 @default.
• W1989690681 cites W1993302385 @default.
• W1989690681 cites W2003516452 @default.
• W1989690681 cites W2005440804 @default.
• W1989690681 cites W2009152737 @default.
• W1989690681 cites W2028439456 @default.
• W1989690681 cites W2037442572 @default.
• W1989690681 cites W2064941025 @default.
• W1989690681 cites W2073676612 @default.
• W1989690681 cites W2081098333 @default.
• W1989690681 cites W2093967060 @default.
• W1989690681 cites W2102934096 @default.
• W1989690681 cites W2103240277 @default.
• W1989690681 cites W2111904037 @default.
• W1989690681 cites W2114830914 @default.
• W1989690681 cites W2122863289 @default.
• W1989690681 cites W2123450550 @default.
• W1989690681 cites W2123836140 @default.
• W1989690681 cites W2129605195 @default.
• W1989690681 cites W2131845382 @default.
• W1989690681 cites W2143634951 @default.
• W1989690681 cites W2166841658 @default.
• W1989690681 cites W2167307690 @default.
• W1989690681 cites W2169062791 @default.
• W1989690681 cites W2915108429 @default.
• W1989690681 cites W2916767477 @default.
• W1989690681 cites W2917375902 @default.
• W1989690681 cites W3036918948 @default.
• W1989690681 cites W2755095224 @default.
• W1989690681 doi "https://doi.org/10.5897/ajpp12.067" @default.
• W1989690681 hasPublicationYear "2012" @default.
• W1989690681 type Work @default.
• W1989690681 sameAs 1989690681 @default.
• W1989690681 citedByCount "0" @default.
• W1989690681 crossrefType "journal-article" @default.
• W1989690681 hasAuthorship W1989690681A5032020402 @default.
• W1989690681 hasAuthorship W1989690681A5047351745 @default.
• W1989690681 hasAuthorship W1989690681A5089470742 @default.
• W1989690681 hasConcept C120665830 @default.
• W1989690681 hasConcept C121332964 @default.
• W1989690681 hasConcept C125705527 @default.
• W1989690681 hasConcept C142669718 @default.
• W1989690681 hasConcept C1491633281 @default.
• W1989690681 hasConcept C169822122 @default.
• W1989690681 hasConcept C2776601116 @default.
• W1989690681 hasConcept C2993400109 @default.
• W1989690681 hasConcept C54355233 @default.
• W1989690681 hasConcept C62478195 @default.
• W1989690681 hasConcept C86803240 @default.
• W1989690681 hasConcept C95444343 @default.
• W1989690681 hasConceptScore W1989690681C120665830 @default.
• W1989690681 hasConceptScore W1989690681C121332964 @default.
• W1989690681 hasConceptScore W1989690681C125705527 @default.
• W1989690681 hasConceptScore W1989690681C142669718 @default.
• W1989690681 hasConceptScore W1989690681C1491633281 @default.
• W1989690681 hasConceptScore W1989690681C169822122 @default.
• W1989690681 hasConceptScore W1989690681C2776601116 @default.
• W1989690681 hasConceptScore W1989690681C2993400109 @default.
• W1989690681 hasConceptScore W1989690681C54355233 @default.
• W1989690681 hasConceptScore W1989690681C62478195 @default.
• W1989690681 hasConceptScore W1989690681C86803240 @default.
• W1989690681 hasConceptScore W1989690681C95444343 @default.
• W1989690681 hasLocation W19896906811 @default.
• W1989690681 hasOpenAccess W1989690681 @default.
• W1989690681 hasPrimaryLocation W19896906811 @default.
• W1989690681 hasRelatedWork W1508840209 @default.
• W1989690681 hasRelatedWork W1534553626 @default.
• W1989690681 hasRelatedWork W2008369123 @default.
• W1989690681 hasRelatedWork W2043494467 @default.
• W1989690681 hasRelatedWork W2064247589 @default.
• W1989690681 hasRelatedWork W2072309400 @default.
• W1989690681 hasRelatedWork W2082209748 @default.
• W1989690681 hasRelatedWork W2083531465 @default.
• W1989690681 hasRelatedWork W2171501785 @default.
• W1989690681 hasRelatedWork W2222388313 @default.
• W1989690681 hasRelatedWork W2257121093 @default.
• W1989690681 hasRelatedWork W2349617162 @default.
• W1989690681 hasRelatedWork W2363417043 @default.
• W1989690681 hasRelatedWork W2408962250 @default.
• W1989690681 hasRelatedWork W2497873156 @default.
• W1989690681 hasRelatedWork W2598741986 @default.
• W1989690681 hasRelatedWork W2997081882 @default.
• W1989690681 hasRelatedWork W3162289733 @default.
• W1989690681 hasRelatedWork W3176138435 @default.
• W1989690681 hasRelatedWork W72983962 @default.
• W1989690681 isParatext "false" @default.
• W1989690681 isRetracted "false" @default.

• next