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- W1989736772 abstract "Abstract The present experiment was designed to determine whether the reversal deficit in nonspatial discrimination tasks following frontal or hippocampal system damage was a result of the spatial components of those tasks, or a general reversal deficit. Rats were trained to choose between two objects based on the stimulus characteristics of the objects themselves; neither the absolute location of the objects in the test arena nor the position of the objects with respect to the rat accurately predicted the correct choice. Rats with either frontal cortex or fimbria-fornix lesions performed worse than controls in both postoperative retention and reversal of the object discrimination. The performance of rats with frontal cortex damage was impaired during the first two postoperative reversals; but not during subsequent reversals. The performance of rats with fornix lesions was impaired only on the first postoperative reversal. These data demonstrate that the nonspatial reversal impairment following damage to either the frontal cortical or hippocampal systems is the result of a general reversal deficit, and is not due to the spatial components of nonspatial tasks." @default.
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- W1989736772 date "1980-01-01" @default.
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- W1989736772 title "Object discrimination by rats: The role of frontal and hippocampal systems in retention and reversal" @default.
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- W1989736772 doi "https://doi.org/10.1016/0031-9384(80)90010-4" @default.
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