Matches in SemOpenAlex for { <https://semopenalex.org/work/W1989738082> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1989738082 endingPage "165" @default.
- W1989738082 startingPage "161" @default.
- W1989738082 abstract "Responses to rat (r) adrenomedullin (ADM) and human (h) ADM were compared in the hindlimb vascular bed of the cat under conditions of controlled blood flow. Intra-arterial injections of rADM and hADM in doses of 0.03-1 nmol caused dose-related decreases in hindlimb perfusion pressure. In terms of relative vasodilator activity, rADM was similar to hADM. The time course of the vasodilator response and the recovery half times (T1/2) for the vasodilator response to rADM and hADM were not significantly different. Decreases in hindlimb perfusion pressure in response to rADM and hADM were not altered by the calcitonin gene-related peptide receptor antagonist, rCGRP(8-37), at the same time, vasodilator responses to calcitonin gene-related peptide (CGRP) were significantly reduced. The T1/2 of the vasodilator response to rADM and hADM were significantly greater after administration of the cAMP-selective, type IV phosphodiesterase inhibitor, rolipram. These data demonstrate that decreases in hindlimb perfusion pressure in response to rADM and hADM are similar and that vasodilator responses to rADM are not dependent on the activation of CGRP receptors in the hindlimb vascular bed of the cat. These data further suggest that decreases in hindlimb perfusion pressure in response to rADM are mediated by smooth muscle increases in cAMP levels." @default.
- W1989738082 created "2016-06-24" @default.
- W1989738082 creator A5014962530 @default.
- W1989738082 creator A5021831733 @default.
- W1989738082 creator A5044328039 @default.
- W1989738082 creator A5054698284 @default.
- W1989738082 creator A5072305918 @default.
- W1989738082 creator A5074803352 @default.
- W1989738082 creator A5086303096 @default.
- W1989738082 date "1997-06-01" @default.
- W1989738082 modified "2023-09-25" @default.
- W1989738082 title "Comparison of responses to rat and human adrenomedullin in the hindlimb vascular bed of the cat" @default.
- W1989738082 cites W1970314104 @default.
- W1989738082 cites W1972441205 @default.
- W1989738082 cites W1982290807 @default.
- W1989738082 cites W2003986516 @default.
- W1989738082 cites W2023333202 @default.
- W1989738082 cites W2024451110 @default.
- W1989738082 cites W2030064280 @default.
- W1989738082 cites W2033697164 @default.
- W1989738082 cites W2042657041 @default.
- W1989738082 cites W2053809255 @default.
- W1989738082 cites W2060000931 @default.
- W1989738082 cites W2062599117 @default.
- W1989738082 cites W2066837470 @default.
- W1989738082 cites W2081267816 @default.
- W1989738082 cites W2092419989 @default.
- W1989738082 cites W2098483384 @default.
- W1989738082 cites W2313122639 @default.
- W1989738082 cites W4234767639 @default.
- W1989738082 cites W4241788459 @default.
- W1989738082 doi "https://doi.org/10.1016/s0167-0115(97)01003-3" @default.
- W1989738082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9272628" @default.
- W1989738082 hasPublicationYear "1997" @default.
- W1989738082 type Work @default.
- W1989738082 sameAs 1989738082 @default.
- W1989738082 citedByCount "20" @default.
- W1989738082 countsByYear W19897380822013 @default.
- W1989738082 countsByYear W19897380822020 @default.
- W1989738082 crossrefType "journal-article" @default.
- W1989738082 hasAuthorship W1989738082A5014962530 @default.
- W1989738082 hasAuthorship W1989738082A5021831733 @default.
- W1989738082 hasAuthorship W1989738082A5044328039 @default.
- W1989738082 hasAuthorship W1989738082A5054698284 @default.
- W1989738082 hasAuthorship W1989738082A5072305918 @default.
- W1989738082 hasAuthorship W1989738082A5074803352 @default.
- W1989738082 hasAuthorship W1989738082A5086303096 @default.
- W1989738082 hasConcept C118303440 @default.
- W1989738082 hasConcept C120770815 @default.
- W1989738082 hasConcept C126322002 @default.
- W1989738082 hasConcept C134018914 @default.
- W1989738082 hasConcept C146957229 @default.
- W1989738082 hasConcept C163170386 @default.
- W1989738082 hasConcept C170493617 @default.
- W1989738082 hasConcept C185592680 @default.
- W1989738082 hasConcept C2777152744 @default.
- W1989738082 hasConcept C2779627488 @default.
- W1989738082 hasConcept C51738704 @default.
- W1989738082 hasConcept C71924100 @default.
- W1989738082 hasConceptScore W1989738082C118303440 @default.
- W1989738082 hasConceptScore W1989738082C120770815 @default.
- W1989738082 hasConceptScore W1989738082C126322002 @default.
- W1989738082 hasConceptScore W1989738082C134018914 @default.
- W1989738082 hasConceptScore W1989738082C146957229 @default.
- W1989738082 hasConceptScore W1989738082C163170386 @default.
- W1989738082 hasConceptScore W1989738082C170493617 @default.
- W1989738082 hasConceptScore W1989738082C185592680 @default.
- W1989738082 hasConceptScore W1989738082C2777152744 @default.
- W1989738082 hasConceptScore W1989738082C2779627488 @default.
- W1989738082 hasConceptScore W1989738082C51738704 @default.
- W1989738082 hasConceptScore W1989738082C71924100 @default.
- W1989738082 hasIssue "2-3" @default.
- W1989738082 hasLocation W19897380821 @default.
- W1989738082 hasLocation W19897380822 @default.
- W1989738082 hasOpenAccess W1989738082 @default.
- W1989738082 hasPrimaryLocation W19897380821 @default.
- W1989738082 hasRelatedWork W2004014618 @default.
- W1989738082 hasRelatedWork W2031603956 @default.
- W1989738082 hasRelatedWork W2071284918 @default.
- W1989738082 hasRelatedWork W2116319226 @default.
- W1989738082 hasRelatedWork W2136463004 @default.
- W1989738082 hasRelatedWork W2169259278 @default.
- W1989738082 hasRelatedWork W2186721510 @default.
- W1989738082 hasRelatedWork W2312430269 @default.
- W1989738082 hasRelatedWork W2409125344 @default.
- W1989738082 hasRelatedWork W4290348824 @default.
- W1989738082 hasVolume "70" @default.
- W1989738082 isParatext "false" @default.
- W1989738082 isRetracted "false" @default.
- W1989738082 magId "1989738082" @default.
- W1989738082 workType "article" @default.