Matches in SemOpenAlex for { <https://semopenalex.org/work/W1989739961> ?p ?o ?g. }
- W1989739961 endingPage "7044" @default.
- W1989739961 startingPage "7040" @default.
- W1989739961 abstract "Mitogenic stimulation of quiescent mouse 3T3 cells with epidermal growth factor leads to biphasic S6 kinase activation. The kinases present in both phases of the response have been purified from 32P-labeled cells and shown to contain a phosphoprotein of equivalent Mr 70,000. Chromatographic analysis of the purified S6 kinases on a Mono Q column reveals that (i) all 32P-labeled protein coelutes with S6 kinase activity, (ii) only those fractions containing S6 kinase autophosphorylate, (iii) autophosphorylation is restricted to a single Mr 70,000 protein, and (iv) the extent of autophosphorylation directly parallels the degree of S6 kinase activation. Analysis of the two autophosphorylated S6 kinases by two-dimensional tryptic phosphopeptide mapping indicates that they are the same protein. Both in vivo 32P-labeled S6 kinases contain phosphoserine and phosphothreonine but no detectable phosphotyrosine. Two-dimensional tryptic peptide maps of the in vivo 32P-labeled S6 kinases are essentially identical, except for a single qualitative change in the late-phase S6 kinase." @default.
- W1989739961 created "2016-06-24" @default.
- W1989739961 creator A5005084447 @default.
- W1989739961 creator A5084022982 @default.
- W1989739961 date "1990-09-01" @default.
- W1989739961 modified "2023-09-25" @default.
- W1989739961 title "Identical Mr 70,000 S6 kinase is activated biphasically by epidermal growth factor: a phosphopeptide that characterizes the late phase." @default.
- W1989739961 cites W1497443740 @default.
- W1989739961 cites W1499420960 @default.
- W1989739961 cites W1499613870 @default.
- W1989739961 cites W1499910068 @default.
- W1989739961 cites W1533778318 @default.
- W1989739961 cites W1541799897 @default.
- W1989739961 cites W154339036 @default.
- W1989739961 cites W1545795848 @default.
- W1989739961 cites W1547198958 @default.
- W1989739961 cites W1578617720 @default.
- W1989739961 cites W1579659728 @default.
- W1989739961 cites W1589101447 @default.
- W1989739961 cites W1595534151 @default.
- W1989739961 cites W1608198953 @default.
- W1989739961 cites W1616609814 @default.
- W1989739961 cites W1657713219 @default.
- W1989739961 cites W1854914172 @default.
- W1989739961 cites W1894641937 @default.
- W1989739961 cites W1941743276 @default.
- W1989739961 cites W1971589551 @default.
- W1989739961 cites W1982861233 @default.
- W1989739961 cites W1987428363 @default.
- W1989739961 cites W1987757198 @default.
- W1989739961 cites W2002623358 @default.
- W1989739961 cites W2009403729 @default.
- W1989739961 cites W2014459225 @default.
- W1989739961 cites W2022658303 @default.
- W1989739961 cites W2023441605 @default.
- W1989739961 cites W2027690266 @default.
- W1989739961 cites W2031744217 @default.
- W1989739961 cites W2034480012 @default.
- W1989739961 cites W2039140238 @default.
- W1989739961 cites W2052810325 @default.
- W1989739961 cites W2053286013 @default.
- W1989739961 cites W2053500972 @default.
- W1989739961 cites W2055042914 @default.
- W1989739961 cites W2057576679 @default.
- W1989739961 cites W2058793161 @default.
- W1989739961 cites W2071548379 @default.
- W1989739961 cites W2083825286 @default.
- W1989739961 cites W2197823034 @default.
- W1989739961 cites W2286453094 @default.
- W1989739961 cites W346505838 @default.
- W1989739961 doi "https://doi.org/10.1073/pnas.87.18.7040" @default.
- W1989739961 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/54678" @default.
- W1989739961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2402489" @default.
- W1989739961 hasPublicationYear "1990" @default.
- W1989739961 type Work @default.
- W1989739961 sameAs 1989739961 @default.
- W1989739961 citedByCount "29" @default.
- W1989739961 crossrefType "journal-article" @default.
- W1989739961 hasAuthorship W1989739961A5005084447 @default.
- W1989739961 hasAuthorship W1989739961A5084022982 @default.
- W1989739961 hasBestOaLocation W19897399611 @default.
- W1989739961 hasConcept C11960822 @default.
- W1989739961 hasConcept C150109051 @default.
- W1989739961 hasConcept C153911025 @default.
- W1989739961 hasConcept C163035849 @default.
- W1989739961 hasConcept C170493617 @default.
- W1989739961 hasConcept C184235292 @default.
- W1989739961 hasConcept C185592680 @default.
- W1989739961 hasConcept C2776362946 @default.
- W1989739961 hasConcept C2776414213 @default.
- W1989739961 hasConcept C2777061661 @default.
- W1989739961 hasConcept C2779933727 @default.
- W1989739961 hasConcept C2780307904 @default.
- W1989739961 hasConcept C55493867 @default.
- W1989739961 hasConcept C82495950 @default.
- W1989739961 hasConcept C86803240 @default.
- W1989739961 hasConcept C95444343 @default.
- W1989739961 hasConcept C97029542 @default.
- W1989739961 hasConceptScore W1989739961C11960822 @default.
- W1989739961 hasConceptScore W1989739961C150109051 @default.
- W1989739961 hasConceptScore W1989739961C153911025 @default.
- W1989739961 hasConceptScore W1989739961C163035849 @default.
- W1989739961 hasConceptScore W1989739961C170493617 @default.
- W1989739961 hasConceptScore W1989739961C184235292 @default.
- W1989739961 hasConceptScore W1989739961C185592680 @default.
- W1989739961 hasConceptScore W1989739961C2776362946 @default.
- W1989739961 hasConceptScore W1989739961C2776414213 @default.
- W1989739961 hasConceptScore W1989739961C2777061661 @default.
- W1989739961 hasConceptScore W1989739961C2779933727 @default.
- W1989739961 hasConceptScore W1989739961C2780307904 @default.
- W1989739961 hasConceptScore W1989739961C55493867 @default.
- W1989739961 hasConceptScore W1989739961C82495950 @default.
- W1989739961 hasConceptScore W1989739961C86803240 @default.
- W1989739961 hasConceptScore W1989739961C95444343 @default.
- W1989739961 hasConceptScore W1989739961C97029542 @default.
- W1989739961 hasIssue "18" @default.
- W1989739961 hasLocation W19897399611 @default.
- W1989739961 hasLocation W19897399612 @default.