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• W1989884911 abstract "The calpains, calcium-activated neutral proteases, play important roles in calcium-regulated intra-cellular signal transduction cascades. Here we report the isolation and initial characterization of a cDNA encoding a calpain 9, digestive tract specific calpain, from catfish taste epithelium. This calpain 9 (Ip-CAPN9a) shares 61% identity with human calpain 9. Phylogenetic analysis provides evidence that catfish calpain 9 and the related enzymes from Oncorhynchus mykiss, Danio rerio, Xenopus laevis, Mus musculus, Rattus norvegicus and Homo sapiens make up a distinct clade within the tissue-specific calpain family. Northern blot analysis reveals that Ip-CAPN9a is predominantly expressed in barbell and digestive tract, but not expressed in brain. An antibody against the N-terminal segment of Ip-CAPN9a recognizes cells within the taste buds in catfish barbells." @default.
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• W1989884911 date "2015-01-01" @default.
• W1989884911 modified "2023-09-30" @default.
• W1989884911 title "Phylogenetic Analysis and Taste Cell Expression of Calpain 9 in Catfish (<i>Ictalurus punctatus</i>)" @default.
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• W1989884911 doi "https://doi.org/10.4236/ns.2015.73016" @default.
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