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- W1989939522 abstract "Bone loss resulting from cancer treatment is an emerging problem among cancer survivors. However, the mechanism andtreatment of cancer treatment-induced bone loss (CTIBL) is not fully understood. The purpose of this article was to review the recentadvances in CTIBL. Methods: A comprehensive review of the literature was conducted. Results: Risk factors for CTIBL that areunique to or commonly found in cancer survivors include chemotherapy-induced menopause, anti-estrogen and anti-androgentherapies, gonadotropin-releasing hormone suppression of gonadal function, and use of glucocorticoids. Assessment of CTIBL is performedusing dual X-ray absorptiometry testing for measurement of BMD levels, Fracture Risk Assessment Tool, and bone turnovermarkers. Initial strategies for prevention of CTIBL include lifestyle modifications such as exercise, an adequate intake of calcium andvitamin D, avoiding tobacco use, and limiting alcohol intake. Pharmacologic therapy should be considered for patients at high risk forbone loss or fracture. Conclusions: Prevention of CTIBL may be the best way to decrease morbidity and financial costs associatedwith osteoporosis and/or fractures. Oncology nurses should be well prepared to identify cancer survivors at risk of CTIBL, and to providethem with education regarding prevention and treatment of CTIBL." @default.
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- W1989939522 date "2013-01-01" @default.
- W1989939522 modified "2023-09-27" @default.
- W1989939522 title "Recent Advances in Management of Cancer Treatment-induced Bone Loss (CTIBL) in Patients with Breast or Prostate Cancer" @default.
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- W1989939522 doi "https://doi.org/10.5388/aon.2013.13.3.103" @default.
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