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- W1989992900 abstract "In order to elucidate the effects of corticosteroids on fetal hearts during midtrimester, pregnant rats were injected with a daily dose of betamethasone (1 mg/kg) from the 12th day through the 17th day of pregnancy. The fetal cardiovascular and pulmonary systems were studied on the 21 st day of pregnancy (term). The treated fetuses showed the following signs of hydrops fetalis: retarded growth, pale, edematous skin, and decreased movement. The thymus and lung displayed prominent hypoplasia. The morphometry of the treated fetuses revealed: decreased right ventricle mass by 37% and decreased left ventricle mass by 29 %. We concluded betamethasone had a significant effect on the developing fetal cardiovascular system, inducing hydrops fetalis. Additionally, betamethasone caused hypoplasia of the thymus and lung" @default.
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- W1989992900 date "1993-01-01" @default.
- W1989992900 modified "2023-10-16" @default.
- W1989992900 title "Cardiovascular and Pulmonary Effects of Betamethasone during Midtrimester on Fetal Rats" @default.
- W1989992900 doi "https://doi.org/10.1159/000263754" @default.
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