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- W1990009013 abstract "The ratio-spectra zero-crossing first- and third-derivative spectrophotometry have been used for determining ternary mixtures of penicillin-G sodium, penicillin-G procain and dihydrostreptomycin sulphate salts. The procedures are accurate, nondestructive and do not require resolutions of equations. In both methods, calibration graphs are linear, with zero-intercept, up to 30 μg ml−1 of penicillin-G sodium and penicillin-G procain, and up to 42 μg ml−1 of dihydrostreptomycin sulphate. r = 0.9999 in each instance. Working wavelengths, 218.5, 211 and 236 nm, respectively, in the first-derivative mode, and 222.5, 311.5 and 242 nm in the third-derivative mode. Detection limits for each drug at p = 0.01 level of significance were calculated to be 0.058, 0.010 and 0.014 μg ml−1 and 0.14, 0.012 and 0.34 μg ml−1, in the first- and third-derivative methods, respectively. Both methods apply favourably to either laboratory mixtures or commercial injections." @default.
- W1990009013 created "2016-06-24" @default.
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- W1990009013 date "1995-03-01" @default.
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- W1990009013 title "Determination of ternary mixtures of antibiotics, by ratio-spectra zero-crossing first- and third-derivative spectrophotometry" @default.
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- W1990009013 doi "https://doi.org/10.1016/0731-7085(95)01250-o" @default.
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