FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990018559> ?p ?o ?g. }

• W1990018559 endingPage "1404" @default.
• W1990018559 startingPage "1399" @default.
• W1990018559 abstract "Immunization of naive mice with beta2-glycoprotein I (beta2GPI) leads to the generation of pathogenic anticardiolipin antibodies associated with clinical manifestations of the antiphospholipid syndrome (APS). The aim of this study was to determine whether immunization of naive mice with human beta2GPI, which shares homology with mouse beta2GPI molecules, breaks tolerance to murine beta2GPI and leads to the generation of anti-mouse beta2GPI.Twenty-four female BALB/c mice were immunized in the footpads with 10 microg of human beta2GPI. Twelve age- and sex-matched BALB/c mice were immunized in the same manner with Freund's complete adjuvant and served as controls. The reactivity of whole sera, polyclonal IgG, and affinity-purified anti-beta2GPI IgG antibodies against human, bovine, and mouse beta2GPI was evaluated by enzyme-linked immunosorbent assay.High titers of anti-human beta2GPI IgG antibodies were detected 1 month after immunization. Progressively increasing titers against murine and bovine beta2GPI were recorded 1-4 months after injection.Immunization of mice with human beta2GPI resulted in the generation of antibodies reacting with human, bovine, and murine beta2GPI. The loss of tolerance to mouse beta2GPI is attributable to the high interspecies homology of beta2GPI. These results may point to molecular mimicry as a possible cause of APS." @default.
• W1990018559 created "2016-06-24" @default.
• W1990018559 creator A5009970788 @default.
• W1990018559 creator A5011545464 @default.
• W1990018559 creator A5012925118 @default.
• W1990018559 creator A5021599110 @default.
• W1990018559 creator A5030466896 @default.
• W1990018559 creator A5031694589 @default.
• W1990018559 creator A5062460945 @default.
• W1990018559 creator A5074738902 @default.
• W1990018559 creator A5079447134 @default.
• W1990018559 creator A5090551729 @default.
• W1990018559 date "2002-05-01" @default.
• W1990018559 modified "2023-10-18" @default.
• W1990018559 title "Immunization of naive BALB/c mice with human ?2-Glycoprotein I breaks tolerance to the murine molecule" @default.
• W1990018559 cites W1934444168 @default.
• W1990018559 cites W1964076193 @default.
• W1990018559 cites W1968519251 @default.
• W1990018559 cites W1976476198 @default.
• W1990018559 cites W1983712801 @default.
• W1990018559 cites W1984176510 @default.
• W1990018559 cites W1984636261 @default.
• W1990018559 cites W2008947652 @default.
• W1990018559 cites W2018948925 @default.
• W1990018559 cites W2025329539 @default.
• W1990018559 cites W2030210438 @default.
• W1990018559 cites W2035121197 @default.
• W1990018559 cites W2039905764 @default.
• W1990018559 cites W2046209839 @default.
• W1990018559 cites W2046961911 @default.
• W1990018559 cites W2047906671 @default.
• W1990018559 cites W2058119805 @default.
• W1990018559 cites W2065025543 @default.
• W1990018559 cites W2078621572 @default.
• W1990018559 cites W2099836298 @default.
• W1990018559 cites W2101831374 @default.
• W1990018559 cites W2113891001 @default.
• W1990018559 cites W2319795850 @default.
• W1990018559 cites W2330553074 @default.
• W1990018559 cites W2405294135 @default.
• W1990018559 cites W40209800 @default.
• W1990018559 doi "https://doi.org/10.1002/art.10304" @default.
• W1990018559 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12115248" @default.
• W1990018559 hasPublicationYear "2002" @default.
• W1990018559 type Work @default.
• W1990018559 sameAs 1990018559 @default.
• W1990018559 citedByCount "24" @default.
• W1990018559 countsByYear W19900185592012 @default.
• W1990018559 countsByYear W19900185592014 @default.
• W1990018559 countsByYear W19900185592015 @default.
• W1990018559 countsByYear W19900185592016 @default.
• W1990018559 countsByYear W19900185592017 @default.
• W1990018559 countsByYear W19900185592019 @default.
• W1990018559 crossrefType "journal-article" @default.
• W1990018559 hasAuthorship W1990018559A5009970788 @default.
• W1990018559 hasAuthorship W1990018559A5011545464 @default.
• W1990018559 hasAuthorship W1990018559A5012925118 @default.
• W1990018559 hasAuthorship W1990018559A5021599110 @default.
• W1990018559 hasAuthorship W1990018559A5030466896 @default.
• W1990018559 hasAuthorship W1990018559A5031694589 @default.
• W1990018559 hasAuthorship W1990018559A5062460945 @default.
• W1990018559 hasAuthorship W1990018559A5074738902 @default.
• W1990018559 hasAuthorship W1990018559A5079447134 @default.
• W1990018559 hasAuthorship W1990018559A5090551729 @default.
• W1990018559 hasConcept C159047783 @default.
• W1990018559 hasConcept C159654299 @default.
• W1990018559 hasConcept C203014093 @default.
• W1990018559 hasConcept C2777863537 @default.
• W1990018559 hasConcept C2778943623 @default.
• W1990018559 hasConcept C2780801004 @default.
• W1990018559 hasConcept C32611913 @default.
• W1990018559 hasConcept C86803240 @default.
• W1990018559 hasConcept C956191 @default.
• W1990018559 hasConceptScore W1990018559C159047783 @default.
• W1990018559 hasConceptScore W1990018559C159654299 @default.
• W1990018559 hasConceptScore W1990018559C203014093 @default.
• W1990018559 hasConceptScore W1990018559C2777863537 @default.
• W1990018559 hasConceptScore W1990018559C2778943623 @default.
• W1990018559 hasConceptScore W1990018559C2780801004 @default.
• W1990018559 hasConceptScore W1990018559C32611913 @default.
• W1990018559 hasConceptScore W1990018559C86803240 @default.
• W1990018559 hasConceptScore W1990018559C956191 @default.
• W1990018559 hasIssue "5" @default.
• W1990018559 hasLocation W19900185591 @default.
• W1990018559 hasLocation W19900185592 @default.
• W1990018559 hasOpenAccess W1990018559 @default.
• W1990018559 hasPrimaryLocation W19900185591 @default.
• W1990018559 hasRelatedWork W1587897575 @default.
• W1990018559 hasRelatedWork W2008839867 @default.
• W1990018559 hasRelatedWork W2061640620 @default.
• W1990018559 hasRelatedWork W2074038286 @default.
• W1990018559 hasRelatedWork W2356268310 @default.
• W1990018559 hasRelatedWork W2359164972 @default.
• W1990018559 hasRelatedWork W2369800411 @default.
• W1990018559 hasRelatedWork W2530813614 @default.
• W1990018559 hasRelatedWork W2978652049 @default.
• W1990018559 hasRelatedWork W4313308905 @default.
• W1990018559 hasVolume "46" @default.

• next