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- W1990030070 abstract "A pathological study of tuberculous tracheobronchitis has been made on 667 cases coming to autopsy at the Chicago Municipal Tuberculosis Sanitarium. Gross evidence of tuberculosis was found in 377 cases (56.5 per cent). Microscopic study of a sample of grossly negative cases gave an estimated figure of 37.5 per cent of lesions in the remaining 290 cases, thereby increasing the positive findings of all cases to 72.0 per cent. Counting only the 87.5 per cent of all far advanced lesions, it is observed that well over 80 per cent of far advanced cases have some degree of tuberculous tracheobronchitis. The incidence was increased in the young age groups and in the female sex. The pathogenesis seemed to be best explained by a direct implantation of bacilli in the mucous glands, or through breaches in the epithelium. The location of lesions in the tracheobronchial tree was more or less random, although points of stress (larynx), posterior aspects of the tracheobronchial tree, and proximity to cavities seemed to be affected most. The distribution of lesions was general in 242 cases (64.7 per cent); 65 (17.3 per cent) in lower portions of the tract; 19 (5.0 per cent) in trachea and left bronchus; 9 (2.4 per cent) in trachea and right bronchus; 31 (8.2 per cent) in trachea alone, and 11 (2.9 per cent) in bronchi alone. The nature of the involvement was diffuse superficial infiltration in 12 cases (3.2 per cent); diffuse and deep infiltration and infiltration and ulceration in 85 cases (22.8 per cent); circumscribed ulceration in 265 cases (70.3 per cent); fibroid stenosis in 5 cases (1.3 per cent); perforation in 6 cases (1.6 per cent), and caseous bronchitis in 4 cases (1.0 per cent). There was microscopic evidence of specific tuberculous lesions in 88.1 per cent of the positive cases studied. The hope for the future of tuberculous tracheobronchitis seems to be for early bronchoscopic study of all cases, early diagnosis, and early treatment of positive cases by thoracoplasty or streptomycin, or both." @default.
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- W1990030070 date "1948-01-01" @default.
- W1990030070 modified "2023-10-14" @default.
- W1990030070 title "Tuberculosis of Trachea and Major Bronchi" @default.
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- W1990030070 doi "https://doi.org/10.1378/chest.14.1.1" @default.
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