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- W1990032320 abstract "An interferometer for measuring dynamic properties of the in vivo tear film on the human cornea has been developed. Thesystem is a near-infrared instantaneous phase-shifting Twyman-Green interferometer. The laser source is a 785 nm solidstatelaser; the system has been carefully designed and calibrated to ensure that the system operates at eye safe levels.Measurements are made over a 6 mm diameter on the cornea. Successive frames of interferometric height measurementsare combined to produce movies showing both the quantitative and qualitative changes in the topography of the tear filmsurface and structure. To date, measurement periods of up to 120 seconds at 28.6 frames per second have been obtained.Several human subjects have been examined using this system, demonstrating a surface height resolution of 25 nm andspatial resolution of 6 μm. Examples of features that have been observed in these in preliminary studies of the tear filminclude: post-blink disruption, evolution, and stabilization of the tear film; tear film artifacts generated by blinking; tearfilm evaporation and break-up; and the propagation of foreign objects in the tear film. This paper discusses theinterferometer design and presents results from in vivo measurements." @default.
- W1990032320 created "2016-06-24" @default.
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- W1990032320 date "2014-08-18" @default.
- W1990032320 modified "2023-09-29" @default.
- W1990032320 title "Dynamic measurement of the corneal tear film with a Twyman-Green interferometer" @default.
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- W1990032320 doi "https://doi.org/10.1117/12.2064431" @default.
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