Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990045305> ?p ?o ?g. }
- W1990045305 endingPage "934" @default.
- W1990045305 startingPage "930" @default.
- W1990045305 abstract "Pancreatic beta-cells are essential for the maintenance of glucose homoeostasis, and dysfunction of these insulin-secreting cells results in the development of diabetes. In the course of events leading from obesity to Type 2 diabetes, several mechanisms are currently envisaged. Among them, lipids and oxidative stress are considered as toxic candidates for the beta-cell. The cellular link between fatty acids and ROS (reactive oxygen species) is essentially the mitochondrion, a key organelle for the control of insulin secretion. Mitochondria are the main source of ROS and are also the primary target of oxidative attacks. The present review presents the current knowledge of lipotoxicity related to oxidative stress in the context of mitochondrial function in the beta-cell." @default.
- W1990045305 created "2016-06-24" @default.
- W1990045305 creator A5006856389 @default.
- W1990045305 creator A5006935079 @default.
- W1990045305 creator A5019550791 @default.
- W1990045305 date "2008-09-19" @default.
- W1990045305 modified "2023-10-01" @default.
- W1990045305 title "The sensitivity of pancreatic β-cells to mitochondrial injuries triggered by lipotoxicity and oxidative stress" @default.
- W1990045305 cites W1482813056 @default.
- W1990045305 cites W1489860413 @default.
- W1990045305 cites W1529592271 @default.
- W1990045305 cites W1598254642 @default.
- W1990045305 cites W1650754258 @default.
- W1990045305 cites W1728066272 @default.
- W1990045305 cites W1921965616 @default.
- W1990045305 cites W1979636493 @default.
- W1990045305 cites W1979754659 @default.
- W1990045305 cites W1981962083 @default.
- W1990045305 cites W1985133999 @default.
- W1990045305 cites W1987183604 @default.
- W1990045305 cites W1987325894 @default.
- W1990045305 cites W1988290009 @default.
- W1990045305 cites W1988540419 @default.
- W1990045305 cites W1992673961 @default.
- W1990045305 cites W1998738935 @default.
- W1990045305 cites W2018185503 @default.
- W1990045305 cites W2019745044 @default.
- W1990045305 cites W2020468088 @default.
- W1990045305 cites W2020816386 @default.
- W1990045305 cites W2028585334 @default.
- W1990045305 cites W2033279283 @default.
- W1990045305 cites W2039821213 @default.
- W1990045305 cites W2044325325 @default.
- W1990045305 cites W2044494908 @default.
- W1990045305 cites W2045380458 @default.
- W1990045305 cites W2046663858 @default.
- W1990045305 cites W2050826311 @default.
- W1990045305 cites W2053827043 @default.
- W1990045305 cites W2057692152 @default.
- W1990045305 cites W2058677692 @default.
- W1990045305 cites W2059467226 @default.
- W1990045305 cites W2065504943 @default.
- W1990045305 cites W2074417648 @default.
- W1990045305 cites W2076510866 @default.
- W1990045305 cites W2079230681 @default.
- W1990045305 cites W2083990676 @default.
- W1990045305 cites W2084703116 @default.
- W1990045305 cites W2088012387 @default.
- W1990045305 cites W2091035564 @default.
- W1990045305 cites W2092551351 @default.
- W1990045305 cites W2096119759 @default.
- W1990045305 cites W2097784879 @default.
- W1990045305 cites W2104622496 @default.
- W1990045305 cites W2105072053 @default.
- W1990045305 cites W2107485860 @default.
- W1990045305 cites W2108791332 @default.
- W1990045305 cites W2109069544 @default.
- W1990045305 cites W2109168147 @default.
- W1990045305 cites W2113007696 @default.
- W1990045305 cites W2114443210 @default.
- W1990045305 cites W2124081028 @default.
- W1990045305 cites W2125068913 @default.
- W1990045305 cites W2132826785 @default.
- W1990045305 cites W2133548838 @default.
- W1990045305 cites W2133561419 @default.
- W1990045305 cites W2140257758 @default.
- W1990045305 cites W2143256430 @default.
- W1990045305 cites W2147993424 @default.
- W1990045305 cites W2156044622 @default.
- W1990045305 cites W2158103448 @default.
- W1990045305 cites W2271272206 @default.
- W1990045305 doi "https://doi.org/10.1042/bst0360930" @default.
- W1990045305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18793163" @default.
- W1990045305 hasPublicationYear "2008" @default.
- W1990045305 type Work @default.
- W1990045305 sameAs 1990045305 @default.
- W1990045305 citedByCount "98" @default.
- W1990045305 countsByYear W19900453052012 @default.
- W1990045305 countsByYear W19900453052013 @default.
- W1990045305 countsByYear W19900453052014 @default.
- W1990045305 countsByYear W19900453052015 @default.
- W1990045305 countsByYear W19900453052016 @default.
- W1990045305 countsByYear W19900453052017 @default.
- W1990045305 countsByYear W19900453052018 @default.
- W1990045305 countsByYear W19900453052019 @default.
- W1990045305 countsByYear W19900453052020 @default.
- W1990045305 countsByYear W19900453052021 @default.
- W1990045305 countsByYear W19900453052022 @default.
- W1990045305 countsByYear W19900453052023 @default.
- W1990045305 crossrefType "journal-article" @default.
- W1990045305 hasAuthorship W1990045305A5006856389 @default.
- W1990045305 hasAuthorship W1990045305A5006935079 @default.
- W1990045305 hasAuthorship W1990045305A5019550791 @default.
- W1990045305 hasConcept C126322002 @default.
- W1990045305 hasConcept C134018914 @default.
- W1990045305 hasConcept C151730666 @default.
- W1990045305 hasConcept C165220095 @default.
- W1990045305 hasConcept C185592680 @default.