Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990065722> ?p ?o ?g. }
- W1990065722 endingPage "630" @default.
- W1990065722 startingPage "621" @default.
- W1990065722 abstract "Paired micropuncture experiments were carried out in plasma-replete volume-expanded rats to examine the acute effects of 1-desamino-8-D-arginine vasopressin (dDAVP) on urinary acidification and tubular handling of bicarbonate and chloride. No effect was detected on the fractional absorption of water, total CO2, and chloride at end-proximal and early distal sites of superficial nephrons in intact animals; dDAVP, however, inhibited the fractional absorption of total CO2 in Henle's loop while stimulating that of chloride in thyroparathyroidectomized (TPTX) somatostatin-infused rats. In the distal tubule accessible to micropuncture, net total CO2 secretion was observed during hypotonic volume expansion, which reversed to net total CO2 absorption during dDAVP infusion in intact Wistar rats. Marked stimulation of urinary acidification occurred in all animals as attested by a fall in urine pH and bicarbonate excretion. Net acid excretion almost doubled in intact rats. We conclude that (a) antidiuretic hormone (ADH) inhibits fractional bicarbonate absorption in the thick ascending limb while stimulating that of chloride at least in TPTX somatostatin-infused rats, and (b) ADH stimulates proton secretion (or inhibits bicarbonate secretion) in the distal tubule and cortical collecting ducts, which leads to enhanced urinary acidification." @default.
- W1990065722 created "2016-06-24" @default.
- W1990065722 creator A5020753395 @default.
- W1990065722 creator A5030271567 @default.
- W1990065722 creator A5036698543 @default.
- W1990065722 creator A5058042986 @default.
- W1990065722 creator A5059624027 @default.
- W1990065722 date "1987-09-01" @default.
- W1990065722 modified "2023-09-26" @default.
- W1990065722 title "Effects of antidiuretic hormone on urinary acidification and on tubular handling of bicarbonate in the rat." @default.
- W1990065722 cites W1861189980 @default.
- W1990065722 cites W1966025469 @default.
- W1990065722 cites W1994348186 @default.
- W1990065722 cites W1996594976 @default.
- W1990065722 cites W2033204727 @default.
- W1990065722 cites W2048819252 @default.
- W1990065722 cites W2053622155 @default.
- W1990065722 cites W2054338131 @default.
- W1990065722 cites W2055681007 @default.
- W1990065722 cites W2061008377 @default.
- W1990065722 cites W2063638897 @default.
- W1990065722 cites W2091671897 @default.
- W1990065722 cites W2128302936 @default.
- W1990065722 cites W2150473935 @default.
- W1990065722 cites W2159274426 @default.
- W1990065722 cites W2163726024 @default.
- W1990065722 cites W2253079696 @default.
- W1990065722 cites W2264048787 @default.
- W1990065722 cites W2269214402 @default.
- W1990065722 cites W2289949345 @default.
- W1990065722 cites W2333655928 @default.
- W1990065722 cites W2336701702 @default.
- W1990065722 cites W2337533611 @default.
- W1990065722 cites W2343129861 @default.
- W1990065722 cites W2396540879 @default.
- W1990065722 cites W2398707352 @default.
- W1990065722 cites W2403793087 @default.
- W1990065722 cites W2408830259 @default.
- W1990065722 cites W2414211092 @default.
- W1990065722 cites W2415478826 @default.
- W1990065722 cites W2415538420 @default.
- W1990065722 cites W2421167333 @default.
- W1990065722 cites W2428471584 @default.
- W1990065722 cites W273969270 @default.
- W1990065722 doi "https://doi.org/10.1172/jci113114" @default.
- W1990065722 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/442283" @default.
- W1990065722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3624481" @default.
- W1990065722 hasPublicationYear "1987" @default.
- W1990065722 type Work @default.
- W1990065722 sameAs 1990065722 @default.
- W1990065722 citedByCount "41" @default.
- W1990065722 countsByYear W19900657222013 @default.
- W1990065722 countsByYear W19900657222014 @default.
- W1990065722 countsByYear W19900657222016 @default.
- W1990065722 countsByYear W19900657222018 @default.
- W1990065722 countsByYear W19900657222019 @default.
- W1990065722 crossrefType "journal-article" @default.
- W1990065722 hasAuthorship W1990065722A5020753395 @default.
- W1990065722 hasAuthorship W1990065722A5030271567 @default.
- W1990065722 hasAuthorship W1990065722A5036698543 @default.
- W1990065722 hasAuthorship W1990065722A5058042986 @default.
- W1990065722 hasAuthorship W1990065722A5059624027 @default.
- W1990065722 hasBestOaLocation W19900657221 @default.
- W1990065722 hasConcept C10146269 @default.
- W1990065722 hasConcept C126322002 @default.
- W1990065722 hasConcept C134018914 @default.
- W1990065722 hasConcept C158171629 @default.
- W1990065722 hasConcept C178790620 @default.
- W1990065722 hasConcept C185592680 @default.
- W1990065722 hasConcept C2776370428 @default.
- W1990065722 hasConcept C2776844834 @default.
- W1990065722 hasConcept C2778695967 @default.
- W1990065722 hasConcept C2779420931 @default.
- W1990065722 hasConcept C2780091579 @default.
- W1990065722 hasConcept C2781112554 @default.
- W1990065722 hasConcept C2781231759 @default.
- W1990065722 hasConcept C71315377 @default.
- W1990065722 hasConcept C71924100 @default.
- W1990065722 hasConcept C86803240 @default.
- W1990065722 hasConceptScore W1990065722C10146269 @default.
- W1990065722 hasConceptScore W1990065722C126322002 @default.
- W1990065722 hasConceptScore W1990065722C134018914 @default.
- W1990065722 hasConceptScore W1990065722C158171629 @default.
- W1990065722 hasConceptScore W1990065722C178790620 @default.
- W1990065722 hasConceptScore W1990065722C185592680 @default.
- W1990065722 hasConceptScore W1990065722C2776370428 @default.
- W1990065722 hasConceptScore W1990065722C2776844834 @default.
- W1990065722 hasConceptScore W1990065722C2778695967 @default.
- W1990065722 hasConceptScore W1990065722C2779420931 @default.
- W1990065722 hasConceptScore W1990065722C2780091579 @default.
- W1990065722 hasConceptScore W1990065722C2781112554 @default.
- W1990065722 hasConceptScore W1990065722C2781231759 @default.
- W1990065722 hasConceptScore W1990065722C71315377 @default.
- W1990065722 hasConceptScore W1990065722C71924100 @default.
- W1990065722 hasConceptScore W1990065722C86803240 @default.
- W1990065722 hasIssue "3" @default.
- W1990065722 hasLocation W19900657221 @default.
- W1990065722 hasLocation W19900657222 @default.