FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990071570> ?p ?o ?g. }

• W1990071570 endingPage "24" @default.
• W1990071570 startingPage "7" @default.
• W1990071570 abstract "The effect of colostral maternal antibodies (Abs), acquired via colostrum, on passive protection and development of systemic and mucosal immune responses against rotavirus was evaluated in neonatal calves. Colostrum-deprived (CD) calves, or calves receiving one dose of pooled control colostrum (CC) or immune colostrum (IC), containing an IgG1 titer to bovine rotavirus (BRV) of 1:16,384 or 1:262,144, respectively, were orally inoculated with 105.5 FFU of IND (P[5]G6) BRV at 2 days of age. Calves were monitored daily for diarrhea, virus shedding and anti-BRV Abs in feces by ELISA. Anti-rotavirus Ab titers in serum were evaluated weekly by isotype-specific ELISA and virus neutralization (VN). At 21 days post-inoculation (dpi), all animals were euthanized and the number of anti-BRV antibody secreting cells (ASC) in intestinal and systemic lymphoid tissues were evaluated by ELISPOT. After colostrum intake, IC calves had significantly higher IgG1 serum titers (GMT=28,526) than CC (GMT=1195) or CD calves (GMT<4). After BRV inoculation, all animals became infected with a mean duration of virus shedding between 6 and 10 days. However, IC calves had significantly fewer days of diarrhea (0.8 days) compared to CD and CC calves (11 and 7 days, respectively). In both groups receiving colostrum there was a delay in the onset of diarrhea and virus shedding associated with IgG1 in feces. In serum and feces, CD and CC calves had peak anti-BRV IgM titers at 7 dpi, but IgA and IgG1 responses were significantly lower in CC calves. Antibody titers detected in serum and feces were associated with circulation of ASC of the same isotype in blood. The IC calves had only an IgM response in feces. At 21 dpi, anti-BRV ASC responses were observed in all analyzed tissues of the three groups, except bone marrow. The intestine was the main site of ASC response against BRV and highest IgA ASC numbers. There was an inverse relationship between passive IgG1 titers and magnitude of ASC responses, with fewer IgG1 ASC in CC calves and significantly lower ASC numbers of all isotypes in IC calves. Thus, passive anti-BRV IgG1 negatively affects active immune responses in a dose-dependent manner. In ileal Peyer’s patches, IgM ASC predominated in calves receiving colostrum; IgG1 ASC predominated in CD calves. The presence in IC calves of IgG1 in feces in the absence of an IgG1 ASC response is consistent with the transfer of serum IgG1 back into the gut contributing to the protection of the intestinal mucosa." @default.
• W1990071570 created "2016-06-24" @default.
• W1990071570 creator A5007657919 @default.
• W1990071570 creator A5014681226 @default.
• W1990071570 creator A5021738815 @default.
• W1990071570 creator A5023390182 @default.
• W1990071570 creator A5034236420 @default.
• W1990071570 creator A5034410752 @default.
• W1990071570 creator A5043090731 @default.
• W1990071570 creator A5053207458 @default.
• W1990071570 creator A5057442349 @default.
• W1990071570 creator A5064559752 @default.
• W1990071570 date "2004-07-01" @default.
• W1990071570 modified "2023-10-12" @default.
• W1990071570 title "Modulation by colostrum-acquired maternal antibodies of systemic and mucosal antibody responses to rotavirus in calves experimentally challenged with bovine rotavirus" @default.
• W1990071570 cites W1534257766 @default.
• W1990071570 cites W1561109643 @default.
• W1990071570 cites W1594237062 @default.
• W1990071570 cites W1906785325 @default.
• W1990071570 cites W1936689035 @default.
• W1990071570 cites W1963758770 @default.
• W1990071570 cites W1964622720 @default.
• W1990071570 cites W1966740583 @default.
• W1990071570 cites W1971388199 @default.
• W1990071570 cites W1982727736 @default.
• W1990071570 cites W1987907874 @default.
• W1990071570 cites W1996715508 @default.
• W1990071570 cites W1996928607 @default.
• W1990071570 cites W2002593667 @default.
• W1990071570 cites W2006588615 @default.
• W1990071570 cites W2016925663 @default.
• W1990071570 cites W2018289835 @default.
• W1990071570 cites W2034293576 @default.
• W1990071570 cites W2035965693 @default.
• W1990071570 cites W2037232743 @default.
• W1990071570 cites W2057583396 @default.
• W1990071570 cites W2060324967 @default.
• W1990071570 cites W2063097158 @default.
• W1990071570 cites W2069978926 @default.
• W1990071570 cites W2071082533 @default.
• W1990071570 cites W2075689961 @default.
• W1990071570 cites W2077035982 @default.
• W1990071570 cites W2079108053 @default.
• W1990071570 cites W2081946612 @default.
• W1990071570 cites W2086296896 @default.
• W1990071570 cites W2095465605 @default.
• W1990071570 cites W2100837269 @default.
• W1990071570 cites W2111462418 @default.
• W1990071570 cites W2113413385 @default.
• W1990071570 cites W2113593120 @default.
• W1990071570 cites W2132241785 @default.
• W1990071570 cites W2133959384 @default.
• W1990071570 cites W2136590857 @default.
• W1990071570 cites W2139560446 @default.
• W1990071570 cites W2143485489 @default.
• W1990071570 cites W2143767364 @default.
• W1990071570 cites W2146513572 @default.
• W1990071570 cites W2147919635 @default.
• W1990071570 cites W2150477303 @default.
• W1990071570 cites W2159759971 @default.
• W1990071570 cites W2240855074 @default.
• W1990071570 cites W2395904387 @default.
• W1990071570 cites W4249810852 @default.
• W1990071570 cites W45802443 @default.
• W1990071570 doi "https://doi.org/10.1016/j.vetimm.2004.02.007" @default.
• W1990071570 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7127479" @default.
• W1990071570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15182992" @default.
• W1990071570 hasPublicationYear "2004" @default.
• W1990071570 type Work @default.
• W1990071570 sameAs 1990071570 @default.
• W1990071570 citedByCount "59" @default.
• W1990071570 countsByYear W19900715702012 @default.
• W1990071570 countsByYear W19900715702013 @default.
• W1990071570 countsByYear W19900715702014 @default.
• W1990071570 countsByYear W19900715702015 @default.
• W1990071570 countsByYear W19900715702016 @default.
• W1990071570 countsByYear W19900715702017 @default.
• W1990071570 countsByYear W19900715702018 @default.
• W1990071570 countsByYear W19900715702019 @default.
• W1990071570 countsByYear W19900715702020 @default.
• W1990071570 countsByYear W19900715702021 @default.
• W1990071570 countsByYear W19900715702022 @default.
• W1990071570 countsByYear W19900715702023 @default.
• W1990071570 crossrefType "journal-article" @default.
• W1990071570 hasAuthorship W1990071570A5007657919 @default.
• W1990071570 hasAuthorship W1990071570A5014681226 @default.
• W1990071570 hasAuthorship W1990071570A5021738815 @default.
• W1990071570 hasAuthorship W1990071570A5023390182 @default.
• W1990071570 hasAuthorship W1990071570A5034236420 @default.
• W1990071570 hasAuthorship W1990071570A5034410752 @default.
• W1990071570 hasAuthorship W1990071570A5043090731 @default.
• W1990071570 hasAuthorship W1990071570A5053207458 @default.
• W1990071570 hasAuthorship W1990071570A5057442349 @default.
• W1990071570 hasAuthorship W1990071570A5064559752 @default.
• W1990071570 hasBestOaLocation W19900715701 @default.
• W1990071570 hasConcept C126322002 @default.
• W1990071570 hasConcept C12914427 @default.
• W1990071570 hasConcept C159047783 @default.

• next