Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990072510> ?p ?o ?g. }
- W1990072510 endingPage "893" @default.
- W1990072510 startingPage "885" @default.
- W1990072510 abstract "We examined the interaction of brain atrophy and white matter lesions (WML) with cognitive functioning in 605 patients (mean age, 58 ± 10; 76% men) with atherosclerotic disease from the Second Manifestations of ARTerial disease-MR substudy (SMART-MR study). Automated brain segmentation was used to quantify volumes of brain tissue, cerebrospinal fluid, and WML on MRI. Total brain, ventricular, and cortical gray matter volume were divided by intracranial volume (ICV). Neuropsychological tests assessing executive functioning and memory performance were performed and composite scores were calculated. We observed that smaller total brain volume, larger ventricular volume, and smaller cortical gray matter volume (all as % of ICV) were associated with worse executive performance and that this association became stronger with presence of brain infarcts or severe WML volume (P-values for interaction <0.05). No interaction between measures of brain volume and cerebrovascular pathology on memory performance was observed. Our findings suggest that patients with cerebrovascular pathology on MRI may be more vulnerable to impairment in executive functioning related to global as well as focal brain atrophy." @default.
- W1990072510 created "2016-06-24" @default.
- W1990072510 creator A5001230537 @default.
- W1990072510 creator A5015441961 @default.
- W1990072510 creator A5015692499 @default.
- W1990072510 creator A5016270487 @default.
- W1990072510 creator A5041498750 @default.
- W1990072510 creator A5042145465 @default.
- W1990072510 date "2011-05-01" @default.
- W1990072510 modified "2023-09-27" @default.
- W1990072510 title "Brain atrophy and cognition: Interaction with cerebrovascular pathology?" @default.
- W1990072510 cites W1538136893 @default.
- W1990072510 cites W1929729372 @default.
- W1990072510 cites W1963694953 @default.
- W1990072510 cites W1971548649 @default.
- W1990072510 cites W1979691956 @default.
- W1990072510 cites W1986159654 @default.
- W1990072510 cites W1992043416 @default.
- W1990072510 cites W1996018537 @default.
- W1990072510 cites W2004752914 @default.
- W1990072510 cites W2007146250 @default.
- W1990072510 cites W2009115047 @default.
- W1990072510 cites W2009483243 @default.
- W1990072510 cites W2009586628 @default.
- W1990072510 cites W2028144674 @default.
- W1990072510 cites W2033143088 @default.
- W1990072510 cites W2035228196 @default.
- W1990072510 cites W2043618136 @default.
- W1990072510 cites W2055077265 @default.
- W1990072510 cites W2056475598 @default.
- W1990072510 cites W2057824887 @default.
- W1990072510 cites W2058063912 @default.
- W1990072510 cites W2089346722 @default.
- W1990072510 cites W2095882961 @default.
- W1990072510 cites W2096656439 @default.
- W1990072510 cites W2102198125 @default.
- W1990072510 cites W2102447768 @default.
- W1990072510 cites W2102887367 @default.
- W1990072510 cites W2110665483 @default.
- W1990072510 cites W2119266884 @default.
- W1990072510 cites W2120962895 @default.
- W1990072510 cites W2122024315 @default.
- W1990072510 cites W2128279838 @default.
- W1990072510 cites W2131078911 @default.
- W1990072510 cites W2131633378 @default.
- W1990072510 cites W2136800398 @default.
- W1990072510 cites W2144625548 @default.
- W1990072510 cites W2157751403 @default.
- W1990072510 cites W2168648323 @default.
- W1990072510 cites W2168758637 @default.
- W1990072510 cites W4296588155 @default.
- W1990072510 doi "https://doi.org/10.1016/j.neurobiolaging.2009.05.005" @default.
- W1990072510 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19520460" @default.
- W1990072510 hasPublicationYear "2011" @default.
- W1990072510 type Work @default.
- W1990072510 sameAs 1990072510 @default.
- W1990072510 citedByCount "61" @default.
- W1990072510 countsByYear W19900725102012 @default.
- W1990072510 countsByYear W19900725102013 @default.
- W1990072510 countsByYear W19900725102014 @default.
- W1990072510 countsByYear W19900725102015 @default.
- W1990072510 countsByYear W19900725102016 @default.
- W1990072510 countsByYear W19900725102017 @default.
- W1990072510 countsByYear W19900725102018 @default.
- W1990072510 countsByYear W19900725102019 @default.
- W1990072510 countsByYear W19900725102020 @default.
- W1990072510 countsByYear W19900725102021 @default.
- W1990072510 countsByYear W19900725102022 @default.
- W1990072510 countsByYear W19900725102023 @default.
- W1990072510 crossrefType "journal-article" @default.
- W1990072510 hasAuthorship W1990072510A5001230537 @default.
- W1990072510 hasAuthorship W1990072510A5015441961 @default.
- W1990072510 hasAuthorship W1990072510A5015692499 @default.
- W1990072510 hasAuthorship W1990072510A5016270487 @default.
- W1990072510 hasAuthorship W1990072510A5041498750 @default.
- W1990072510 hasAuthorship W1990072510A5042145465 @default.
- W1990072510 hasConcept C101070640 @default.
- W1990072510 hasConcept C126322002 @default.
- W1990072510 hasConcept C126838900 @default.
- W1990072510 hasConcept C14216870 @default.
- W1990072510 hasConcept C142724271 @default.
- W1990072510 hasConcept C143409427 @default.
- W1990072510 hasConcept C146638467 @default.
- W1990072510 hasConcept C15744967 @default.
- W1990072510 hasConcept C164705383 @default.
- W1990072510 hasConcept C169760540 @default.
- W1990072510 hasConcept C169900460 @default.
- W1990072510 hasConcept C2779651940 @default.
- W1990072510 hasConcept C2781172350 @default.
- W1990072510 hasConcept C2781192897 @default.
- W1990072510 hasConcept C536788834 @default.
- W1990072510 hasConcept C65835030 @default.
- W1990072510 hasConcept C71924100 @default.
- W1990072510 hasConceptScore W1990072510C101070640 @default.
- W1990072510 hasConceptScore W1990072510C126322002 @default.
- W1990072510 hasConceptScore W1990072510C126838900 @default.
- W1990072510 hasConceptScore W1990072510C14216870 @default.
- W1990072510 hasConceptScore W1990072510C142724271 @default.