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- W1990095133 abstract "Mathematical modeling is a vital tool for studying biological systems. Due to the system complexity and technical challenges in molecular level measurement, it is commonly the case that a large number of model parameters have uncertain values. Analyzing model dynamics from a single estimated parameter set is insufficient and liable for misleading results. Global sensitivity analysis (GSA) has been recommended as a must-have step in the process of developing reliable models. However, the technique comes at high computation costs as it is based on Monte Carlo simulation which requires a large number of model evaluations and manipulating on massive data for sensitivity estimation. In this work, we develop a software package for global sensitivity estimation of biological models. The software is deployed on KISTI high performance computing (HPC) cluster environment to provide web-service to system biology modelers." @default.
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- W1990095133 date "2012-11-01" @default.
- W1990095133 modified "2023-10-05" @default.
- W1990095133 title "A distributed software package for global sensitivity analysis of biological models" @default.
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- W1990095133 doi "https://doi.org/10.1109/bibe.2012.6399724" @default.
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