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- W1990096722 abstract "A simple and straightforward synthesis of 1-substituted-4-aryl-5-fluoro-1,2,3,6-tetrahydropyridine (3) or 1-substituted 4-diarylmethanoyl-4-fluoropiperidine (6) by the treatment of piperidinyl exo- or endo-olefin with 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate (Selectfluor) is reported. Two transformations from endo-olefin 1 to allylic fluoride 3 and from exo-olefin 2 to fluorohydrin 6 proceed via allylic fluorination and fluorohydroxylation in moderate yields. It presents two novel reactions promoted by Selectfluor and broadens the scope of application." @default.
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- W1990096722 date "2010-11-01" @default.
- W1990096722 modified "2023-10-18" @default.
- W1990096722 title "Selectfluor-promoted fluorination of piperidinyl olefins" @default.
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- W1990096722 doi "https://doi.org/10.1016/j.tetlet.2010.08.090" @default.
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