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- W1990115242 abstract "L'inactivation des sulfamides et du trimethoprime par les milieux peptonés est liée à la présence d'inhibiteurs, en particulier thymidine. La thymidine-phosphorylase apportée par le sang de cheval hémolysé les neutralise. Les souches de Bacilles gram négatif testées apparaissent plus résistantes aux sulfamides et trimethoprime sur Mueller-Hinton que sur Mueller-Hinton au sang de cheval hémolysé. Les milieux utilisés pour tester sulfamides ou trimethoprime ne doivent pas contenir de thymidine : utilisation de milieu sans thymidine ou adjonction de sang de cheval hémolysé pour la neutraliser. The inactivation of sulphonamides and trimethoprim by peptone containing medium is due to the presence of inhibitors (especially thymidine). Thymidine-phosphorylase contained in lysed horseblood neutralises them. Strains of gram negative bacilli are more resistant to sulphonamides and trimethoprim on Mueller-Hinton that on Mueller-Hinton with lysed blood agar. Medium to be used with sulphonamides and trimethoprim must therefore either be prepared from thymidine-free ingredients or appropriately treated to render it so." @default.
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- W1990115242 date "1980-10-01" @default.
- W1990115242 modified "2023-09-27" @default.
- W1990115242 title "Etude de la sensibilité de bacilles gram négatif au Sulfamethoxazole et au Trimethoprime. Influence de la composition du milieu" @default.
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- W1990115242 doi "https://doi.org/10.1016/s0399-077x(80)80130-2" @default.
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