Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990147104> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W1990147104 endingPage "815" @default.
- W1990147104 startingPage "810" @default.
- W1990147104 abstract "A liquid chromatography-tandem mass spectrometric (LC/MS/MS) method was developed for the determination of a selective Na(+)/H(+) exchanger inhibitor 4-cyano(benzo[b]thiophene-2-carbonyl)guanidine (KR-33028) in rat plasma. KR-33028 and the internal standard, linezolid, were extracted from rat plasma with ethyl acetate at neutral pH. The analytes were separated on an XBridge C(18) column with a mixture of methanol-0.1% formic acid (35:65, v/v) as mobile phase and detected using an electrospray ionization tandem mass spectrometry in the multiple-reaction-monitoring mode. The standard curve was linear (r = 0.9998) over the concentration range of 2.0-1000 ng/mL. The coefficients of variation of intra- and inter-assay were 1.3-6.8% and the relative error was 0.8-5.0%. The recoveries of KR-33028 and linezolid were 70.5 and 84.6%, respectively. The lower limit of quantification for KR-33028 was 2.0 ng/mL using 50 microL plasma sample. This method was successfully applied to the pharmacokinetic study of KR-33028 in rats." @default.
- W1990147104 created "2016-06-24" @default.
- W1990147104 creator A5017943773 @default.
- W1990147104 creator A5038208009 @default.
- W1990147104 creator A5041053589 @default.
- W1990147104 creator A5048066309 @default.
- W1990147104 creator A5048145361 @default.
- W1990147104 creator A5068039063 @default.
- W1990147104 creator A5071322957 @default.
- W1990147104 date "2007-01-01" @default.
- W1990147104 modified "2023-10-16" @default.
- W1990147104 title "Determination of a selective Na+/H+ exchanger inhibitor, 4-cyano(benzo[b]thiophene-2-carbonyl)guanidine (KR-33028) in rat plasma by liquid chromatography–tandem mass spectrometry" @default.
- W1990147104 cites W1976820687 @default.
- W1990147104 cites W1988291158 @default.
- W1990147104 cites W2009942091 @default.
- W1990147104 cites W2011345736 @default.
- W1990147104 cites W2028771588 @default.
- W1990147104 cites W2040139510 @default.
- W1990147104 cites W2049907643 @default.
- W1990147104 cites W2050226999 @default.
- W1990147104 cites W2055271975 @default.
- W1990147104 cites W2070117143 @default.
- W1990147104 cites W2081892357 @default.
- W1990147104 cites W2087784543 @default.
- W1990147104 cites W2130413670 @default.
- W1990147104 cites W2951465382 @default.
- W1990147104 doi "https://doi.org/10.1002/bmc.806" @default.
- W1990147104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17428008" @default.
- W1990147104 hasPublicationYear "2007" @default.
- W1990147104 type Work @default.
- W1990147104 sameAs 1990147104 @default.
- W1990147104 citedByCount "5" @default.
- W1990147104 countsByYear W19901471042013 @default.
- W1990147104 crossrefType "journal-article" @default.
- W1990147104 hasAuthorship W1990147104A5017943773 @default.
- W1990147104 hasAuthorship W1990147104A5038208009 @default.
- W1990147104 hasAuthorship W1990147104A5041053589 @default.
- W1990147104 hasAuthorship W1990147104A5048066309 @default.
- W1990147104 hasAuthorship W1990147104A5048145361 @default.
- W1990147104 hasAuthorship W1990147104A5068039063 @default.
- W1990147104 hasAuthorship W1990147104A5071322957 @default.
- W1990147104 hasConcept C119128265 @default.
- W1990147104 hasConcept C162356407 @default.
- W1990147104 hasConcept C185592680 @default.
- W1990147104 hasConcept C2777379063 @default.
- W1990147104 hasConcept C31827203 @default.
- W1990147104 hasConcept C40684141 @default.
- W1990147104 hasConcept C43617362 @default.
- W1990147104 hasConcept C71043704 @default.
- W1990147104 hasConceptScore W1990147104C119128265 @default.
- W1990147104 hasConceptScore W1990147104C162356407 @default.
- W1990147104 hasConceptScore W1990147104C185592680 @default.
- W1990147104 hasConceptScore W1990147104C2777379063 @default.
- W1990147104 hasConceptScore W1990147104C31827203 @default.
- W1990147104 hasConceptScore W1990147104C40684141 @default.
- W1990147104 hasConceptScore W1990147104C43617362 @default.
- W1990147104 hasConceptScore W1990147104C71043704 @default.
- W1990147104 hasIssue "8" @default.
- W1990147104 hasLocation W19901471041 @default.
- W1990147104 hasLocation W19901471042 @default.
- W1990147104 hasOpenAccess W1990147104 @default.
- W1990147104 hasPrimaryLocation W19901471041 @default.
- W1990147104 hasRelatedWork W1277187992 @default.
- W1990147104 hasRelatedWork W1558772439 @default.
- W1990147104 hasRelatedWork W2079130042 @default.
- W1990147104 hasRelatedWork W2148112117 @default.
- W1990147104 hasRelatedWork W2517618103 @default.
- W1990147104 hasRelatedWork W2791978427 @default.
- W1990147104 hasRelatedWork W2936345590 @default.
- W1990147104 hasRelatedWork W2979742567 @default.
- W1990147104 hasRelatedWork W3194462057 @default.
- W1990147104 hasRelatedWork W4238213830 @default.
- W1990147104 hasVolume "21" @default.
- W1990147104 isParatext "false" @default.
- W1990147104 isRetracted "false" @default.
- W1990147104 magId "1990147104" @default.
- W1990147104 workType "article" @default.