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- W1990163912 abstract "The biotransformation of 3β-acetoxypregna-5,16-diene-20-one (1) by using a filamentous fungus Penicillium citrinum resulted in the production of four metabolites 2-5. The structures of these compounds were elucidated by different spectroscopic analysis (1D- and 2D-NMR) and HR-ESI-MS as 3β,7β-dihydroxy-pregn-5,16(17)-dien-20-one (2), 3β-hydroxy-7α-methoxy-pregn-5,16(17)-dien-20-one (3), 3β,7β,11α-trihydroxy-pregn-5,16(17)-dien-20-one (4), and a known 3β,7α-dihydroxy-pregn-5,16(17)-dien-20-one (5). The 7-O-methylation is a novel reaction in the field of microbial transformation of pregnane steroids." @default.
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- W1990163912 date "2011-01-01" @default.
- W1990163912 modified "2023-09-29" @default.
- W1990163912 title "Microbial transformation of 3β-acetoxypregna-5,16-diene-20-one by Penicillium citrinum" @default.
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- W1990163912 doi "https://doi.org/10.1016/j.steroids.2010.08.006" @default.
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