Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990165205> ?p ?o ?g. }
- W1990165205 endingPage "13" @default.
- W1990165205 startingPage "1" @default.
- W1990165205 abstract "Studies showed that specific probiotics provide therapeutic benefits in inflammatory bowel disease. In vitro evidence suggested that Lactobacillus paracasei also called ST11 (CNCM I-2116) is a potent strain with immune modulation properties. However, little is known about its capacity to alleviate inflammatory symptoms in vivo In this context, the main objective of this study was to investigate the role of ST11 on intestinal inflammation using the adoptive transfer mouse model of experimental colitis. Rag2 -/- recipient mice were fed with ST11 (10 9 CFU/day)a month prior toinduce colitis by adoptive transfer of naive T cells. One month later, in clear contrast to nonfed mice, weight loss was significantly reduced by 50% in ST11-fed mice. Further analysis of colon specimens revealed a significant reduction neutrophil infiltration and mucosal expression of IL1 β , IL-6, and IL12 proinflammatory cytokines, whereas no consistent differences in expression of antibacterial peptides or tight junction proteins were observed between PBS and ST11-fed mice. All together, our results demonstrate that oral administration of ST11 was safe and had a significant preventive effect on colitis. We conclude that probiotics such as Lactobacillus paracasei harbor worthwhile in vivo immunomodulatory properties to prevent intestinal inflammation by nutritional approaches." @default.
- W1990165205 created "2016-06-24" @default.
- W1990165205 creator A5001238139 @default.
- W1990165205 creator A5013089558 @default.
- W1990165205 creator A5014182991 @default.
- W1990165205 creator A5028007643 @default.
- W1990165205 creator A5047598212 @default.
- W1990165205 creator A5061062877 @default.
- W1990165205 creator A5066971460 @default.
- W1990165205 creator A5068995489 @default.
- W1990165205 creator A5089833360 @default.
- W1990165205 date "2011-01-01" @default.
- W1990165205 modified "2023-10-14" @default.
- W1990165205 title "<i>Lactobacillus paracasei</i>Reduces Intestinal Inflammation in Adoptive Transfer Mouse Model of Experimental Colitis" @default.
- W1990165205 cites W1498031631 @default.
- W1990165205 cites W1909331175 @default.
- W1990165205 cites W1941112737 @default.
- W1990165205 cites W1964227583 @default.
- W1990165205 cites W1965655960 @default.
- W1990165205 cites W1971119469 @default.
- W1990165205 cites W1972886167 @default.
- W1990165205 cites W1978039873 @default.
- W1990165205 cites W1981859401 @default.
- W1990165205 cites W1985462428 @default.
- W1990165205 cites W1993078298 @default.
- W1990165205 cites W1999283406 @default.
- W1990165205 cites W2002061924 @default.
- W1990165205 cites W2005553679 @default.
- W1990165205 cites W2014895337 @default.
- W1990165205 cites W2018359273 @default.
- W1990165205 cites W2020853672 @default.
- W1990165205 cites W2028935045 @default.
- W1990165205 cites W2034016494 @default.
- W1990165205 cites W2036746772 @default.
- W1990165205 cites W2039605189 @default.
- W1990165205 cites W2059149560 @default.
- W1990165205 cites W2060515799 @default.
- W1990165205 cites W2062363040 @default.
- W1990165205 cites W2075816488 @default.
- W1990165205 cites W2077926569 @default.
- W1990165205 cites W2086454098 @default.
- W1990165205 cites W2087887844 @default.
- W1990165205 cites W2091990208 @default.
- W1990165205 cites W2099405019 @default.
- W1990165205 cites W2100842618 @default.
- W1990165205 cites W2103431821 @default.
- W1990165205 cites W2103600875 @default.
- W1990165205 cites W2109509831 @default.
- W1990165205 cites W2112866067 @default.
- W1990165205 cites W2115625081 @default.
- W1990165205 cites W2116286418 @default.
- W1990165205 cites W2117015448 @default.
- W1990165205 cites W2118081432 @default.
- W1990165205 cites W2132867804 @default.
- W1990165205 cites W2145516472 @default.
- W1990165205 cites W2148455779 @default.
- W1990165205 cites W2159987542 @default.
- W1990165205 cites W2160268203 @default.
- W1990165205 cites W2161850800 @default.
- W1990165205 cites W2163489226 @default.
- W1990165205 cites W2166236498 @default.
- W1990165205 cites W2168674294 @default.
- W1990165205 cites W4211241312 @default.
- W1990165205 doi "https://doi.org/10.1155/2011/807483" @default.
- W1990165205 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3145352" @default.
- W1990165205 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21808650" @default.
- W1990165205 hasPublicationYear "2011" @default.
- W1990165205 type Work @default.
- W1990165205 sameAs 1990165205 @default.
- W1990165205 citedByCount "28" @default.
- W1990165205 countsByYear W19901652052012 @default.
- W1990165205 countsByYear W19901652052013 @default.
- W1990165205 countsByYear W19901652052014 @default.
- W1990165205 countsByYear W19901652052015 @default.
- W1990165205 countsByYear W19901652052016 @default.
- W1990165205 countsByYear W19901652052017 @default.
- W1990165205 countsByYear W19901652052019 @default.
- W1990165205 countsByYear W19901652052020 @default.
- W1990165205 countsByYear W19901652052021 @default.
- W1990165205 countsByYear W19901652052022 @default.
- W1990165205 countsByYear W19901652052023 @default.
- W1990165205 crossrefType "journal-article" @default.
- W1990165205 hasAuthorship W1990165205A5001238139 @default.
- W1990165205 hasAuthorship W1990165205A5013089558 @default.
- W1990165205 hasAuthorship W1990165205A5014182991 @default.
- W1990165205 hasAuthorship W1990165205A5028007643 @default.
- W1990165205 hasAuthorship W1990165205A5047598212 @default.
- W1990165205 hasAuthorship W1990165205A5061062877 @default.
- W1990165205 hasAuthorship W1990165205A5066971460 @default.
- W1990165205 hasAuthorship W1990165205A5068995489 @default.
- W1990165205 hasAuthorship W1990165205A5089833360 @default.
- W1990165205 hasBestOaLocation W19901652051 @default.
- W1990165205 hasConcept C100544194 @default.
- W1990165205 hasConcept C126322002 @default.
- W1990165205 hasConcept C150903083 @default.
- W1990165205 hasConcept C151730666 @default.
- W1990165205 hasConcept C164027704 @default.
- W1990165205 hasConcept C203014093 @default.