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- W1990171875 abstract "Imipenem-cilastatin was compared, in two multicentre clinical trials, with cefazolin or cephalothin, in their efficacy, safety, and tolerance. Safety and tolerance for imipenem-cilastatin was similar to that of these two cephalosporins. There were more transient liver function test changes in the imipenem-cilastatin group, but the frequency was similar to that for beta-lactams in general. There were similar numbers of cases of transient neutropenia in each group. Clinical side effects were few for the treatment groups and all drugs were well tolerated." @default.
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- W1990171875 date "1983-01-01" @default.
- W1990171875 modified "2023-09-23" @default.
- W1990171875 title "Safety and tolerance comparison of imipenem-cilastatin to cephalothin and cefazolin" @default.
- W1990171875 doi "https://doi.org/10.1093/jac/12.suppl_d.125" @default.
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