FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990199992> ?p ?o ?g. }

• W1990199992 endingPage "654" @default.
• W1990199992 startingPage "637" @default.
• W1990199992 abstract "Mechanosensory hair cells are essential for audition in vertebrates, and in many species, have the capacity for regeneration when damaged. Regeneration is robust in the fish lateral line system as new hair cells can reappear after damage induced by waterborne aminoglycoside antibiotics, platinum-based drugs, and heavy metals. Here, we characterize the loss and reappearance of lateral line hair cells induced in zebrafish larvae treated with copper sulfate using diverse molecular markers. Transgenic fish that express green fluorescent protein in different cell types in the lateral line system have allowed us to follow the regeneration of hair cells after different damage protocols. We show that conditions that damage only differentiated hair cells lead to reappearance of new hair cells within 24 h from nondividing precursors, whereas harsher conditions are followed by a longer recovery period that is accompanied by extensive cell division. In order to characterize the cell population that gives rise to new hair cells, we describe the expression of a neural stem cell marker in neuromasts. The zebrafish sox2 gene is strongly expressed in neuromast progenitor cells, including those of the migrating lateral line primordium, the accessory cells that underlie the hair cells in neuromasts, and in interneuromastic cells that give rise to new neuromasts. Moreover, we find that most of the cells that proliferate within the neuromast during regeneration express this marker. Thus, our results describe the dynamics of hair cell regeneration in zebrafish and suggest the existence of at least two mechanisms for recovery of these cells in neuromasts." @default.
• W1990199992 created "2016-06-24" @default.
• W1990199992 creator A5010193084 @default.
• W1990199992 creator A5042023466 @default.
• W1990199992 creator A5048805238 @default.
• W1990199992 creator A5081166069 @default.
• W1990199992 creator A5087600682 @default.
• W1990199992 date "2007-04-01" @default.
• W1990199992 modified "2023-09-27" @default.
• W1990199992 title "Regeneration in zebrafish lateral line neuromasts: Expression of the neural progenitor cell marker sox2 and proliferation-dependent and-independent mechanisms of hair cell renewal" @default.
• W1990199992 cites W1540057367 @default.
• W1990199992 cites W1829932518 @default.
• W1990199992 cites W1929144684 @default.
• W1990199992 cites W1963506121 @default.
• W1990199992 cites W1966010532 @default.
• W1990199992 cites W1971757408 @default.
• W1990199992 cites W1975527788 @default.
• W1990199992 cites W1976318182 @default.
• W1990199992 cites W1983498842 @default.
• W1990199992 cites W1983620155 @default.
• W1990199992 cites W1984830616 @default.
• W1990199992 cites W2006723548 @default.
• W1990199992 cites W2010837729 @default.
• W1990199992 cites W2015842193 @default.
• W1990199992 cites W2019790479 @default.
• W1990199992 cites W2021270991 @default.
• W1990199992 cites W2021697970 @default.
• W1990199992 cites W2025047543 @default.
• W1990199992 cites W2026120980 @default.
• W1990199992 cites W2026805828 @default.
• W1990199992 cites W2027628438 @default.
• W1990199992 cites W2028916500 @default.
• W1990199992 cites W2029615653 @default.
• W1990199992 cites W2033010198 @default.
• W1990199992 cites W2037829284 @default.
• W1990199992 cites W2037996951 @default.
• W1990199992 cites W2043203355 @default.
• W1990199992 cites W2050377476 @default.
• W1990199992 cites W2054378694 @default.
• W1990199992 cites W2057995143 @default.
• W1990199992 cites W2080579969 @default.
• W1990199992 cites W2083329120 @default.
• W1990199992 cites W2086693994 @default.
• W1990199992 cites W2091508032 @default.
• W1990199992 cites W2092930161 @default.
• W1990199992 cites W2095872630 @default.
• W1990199992 cites W2105493567 @default.
• W1990199992 cites W2110737176 @default.
• W1990199992 cites W2113278451 @default.
• W1990199992 cites W2122875021 @default.
• W1990199992 cites W2123938765 @default.
• W1990199992 cites W2125349610 @default.
• W1990199992 cites W2130814212 @default.
• W1990199992 cites W2137701107 @default.
• W1990199992 cites W2163857939 @default.
• W1990199992 cites W2183683773 @default.
• W1990199992 cites W2506755659 @default.
• W1990199992 doi "https://doi.org/10.1002/dneu.20386" @default.
• W1990199992 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17443814" @default.
• W1990199992 hasPublicationYear "2007" @default.
• W1990199992 type Work @default.
• W1990199992 sameAs 1990199992 @default.
• W1990199992 citedByCount "144" @default.
• W1990199992 countsByYear W19901999922012 @default.
• W1990199992 countsByYear W19901999922013 @default.
• W1990199992 countsByYear W19901999922014 @default.
• W1990199992 countsByYear W19901999922015 @default.
• W1990199992 countsByYear W19901999922016 @default.
• W1990199992 countsByYear W19901999922017 @default.
• W1990199992 countsByYear W19901999922018 @default.
• W1990199992 countsByYear W19901999922019 @default.
• W1990199992 countsByYear W19901999922020 @default.
• W1990199992 countsByYear W19901999922021 @default.
• W1990199992 countsByYear W19901999922022 @default.
• W1990199992 countsByYear W19901999922023 @default.
• W1990199992 crossrefType "journal-article" @default.
• W1990199992 hasAuthorship W1990199992A5010193084 @default.
• W1990199992 hasAuthorship W1990199992A5042023466 @default.
• W1990199992 hasAuthorship W1990199992A5048805238 @default.
• W1990199992 hasAuthorship W1990199992A5081166069 @default.
• W1990199992 hasAuthorship W1990199992A5087600682 @default.
• W1990199992 hasConcept C104317684 @default.
• W1990199992 hasConcept C105702510 @default.
• W1990199992 hasConcept C148738053 @default.
• W1990199992 hasConcept C171056886 @default.
• W1990199992 hasConcept C201750760 @default.
• W1990199992 hasConcept C2776878037 @default.
• W1990199992 hasConcept C2777933648 @default.
• W1990199992 hasConcept C2778585322 @default.
• W1990199992 hasConcept C2780130748 @default.
• W1990199992 hasConcept C28328180 @default.
• W1990199992 hasConcept C53273792 @default.
• W1990199992 hasConcept C54355233 @default.
• W1990199992 hasConcept C86339819 @default.
• W1990199992 hasConcept C86803240 @default.
• W1990199992 hasConcept C95444343 @default.
• W1990199992 hasConceptScore W1990199992C104317684 @default.
• W1990199992 hasConceptScore W1990199992C105702510 @default.

• next