Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990207169> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1990207169 endingPage "621" @default.
- W1990207169 startingPage "617" @default.
- W1990207169 abstract "Anisatin, a toxic sesquiterpene isolated from the Japanese star anise (Illicium anisatum L.), competitively inhibited the specific binding of [3H]4'-ethynyl-4-n-propylbicycloorthobenzoate ([3H]EBOB), a non-competitive antagonist of gamma-aminobutyric acid (GABA)A receptors, to rat brain membranes with an IC50 value of 0.43 microM. R 5135, a competitive GABA antagonist, decreased the potency of anisatin in inhibiting [3H]EBOB binding in a negatively cooperative manner. Two other competitive antagonists, SR 95531 (gabazine) and (-)-bicuculline methiodide, had similar effects. On the other hand, R 5135 exerted little influence on the potencies of the other non-competitive antagonists tested: EBOB, picrotoxinin, isopropylbicyclophosphate, and dieldrin. Thus, anisatin was clearly different from the other non-competitive antagonists in responding to the action of competitive antagonists on (GABA)A receptors. These findings suggest that the binding region of anisatin might overlap with that of the other non-competitive antagonists, but that anisatin must interact with other specific region(s)." @default.
- W1990207169 created "2016-06-24" @default.
- W1990207169 creator A5026309229 @default.
- W1990207169 creator A5040715675 @default.
- W1990207169 creator A5048715037 @default.
- W1990207169 creator A5071302764 @default.
- W1990207169 date "1999-08-01" @default.
- W1990207169 modified "2023-09-24" @default.
- W1990207169 title "Interaction of anisatin with rat brain γ-aminobutyric acida receptors: allosteric modulation by competitive antagonists" @default.
- W1990207169 cites W1605013614 @default.
- W1990207169 cites W1971340038 @default.
- W1990207169 cites W1988918690 @default.
- W1990207169 cites W1997967494 @default.
- W1990207169 cites W2004010919 @default.
- W1990207169 cites W2004942252 @default.
- W1990207169 cites W2010944850 @default.
- W1990207169 cites W2028885556 @default.
- W1990207169 cites W2040742860 @default.
- W1990207169 cites W2042942158 @default.
- W1990207169 cites W2056190454 @default.
- W1990207169 cites W2058896100 @default.
- W1990207169 cites W2065722216 @default.
- W1990207169 cites W2088814430 @default.
- W1990207169 cites W2101446007 @default.
- W1990207169 cites W2143919588 @default.
- W1990207169 cites W2322779173 @default.
- W1990207169 cites W2328734883 @default.
- W1990207169 cites W2952385117 @default.
- W1990207169 doi "https://doi.org/10.1016/s0006-2952(99)00129-x" @default.
- W1990207169 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10413298" @default.
- W1990207169 hasPublicationYear "1999" @default.
- W1990207169 type Work @default.
- W1990207169 sameAs 1990207169 @default.
- W1990207169 citedByCount "22" @default.
- W1990207169 countsByYear W19902071692012 @default.
- W1990207169 countsByYear W19902071692014 @default.
- W1990207169 countsByYear W19902071692016 @default.
- W1990207169 countsByYear W19902071692018 @default.
- W1990207169 countsByYear W19902071692020 @default.
- W1990207169 countsByYear W19902071692023 @default.
- W1990207169 crossrefType "journal-article" @default.
- W1990207169 hasAuthorship W1990207169A5026309229 @default.
- W1990207169 hasAuthorship W1990207169A5040715675 @default.
- W1990207169 hasAuthorship W1990207169A5048715037 @default.
- W1990207169 hasAuthorship W1990207169A5071302764 @default.
- W1990207169 hasConcept C107824862 @default.
- W1990207169 hasConcept C150757390 @default.
- W1990207169 hasConcept C166342909 @default.
- W1990207169 hasConcept C168258287 @default.
- W1990207169 hasConcept C170493617 @default.
- W1990207169 hasConcept C181199279 @default.
- W1990207169 hasConcept C185592680 @default.
- W1990207169 hasConcept C2776885963 @default.
- W1990207169 hasConcept C2780763569 @default.
- W1990207169 hasConcept C55493867 @default.
- W1990207169 hasConcept C71240020 @default.
- W1990207169 hasConcept C79636183 @default.
- W1990207169 hasConcept C86803240 @default.
- W1990207169 hasConcept C86811712 @default.
- W1990207169 hasConcept C98274493 @default.
- W1990207169 hasConceptScore W1990207169C107824862 @default.
- W1990207169 hasConceptScore W1990207169C150757390 @default.
- W1990207169 hasConceptScore W1990207169C166342909 @default.
- W1990207169 hasConceptScore W1990207169C168258287 @default.
- W1990207169 hasConceptScore W1990207169C170493617 @default.
- W1990207169 hasConceptScore W1990207169C181199279 @default.
- W1990207169 hasConceptScore W1990207169C185592680 @default.
- W1990207169 hasConceptScore W1990207169C2776885963 @default.
- W1990207169 hasConceptScore W1990207169C2780763569 @default.
- W1990207169 hasConceptScore W1990207169C55493867 @default.
- W1990207169 hasConceptScore W1990207169C71240020 @default.
- W1990207169 hasConceptScore W1990207169C79636183 @default.
- W1990207169 hasConceptScore W1990207169C86803240 @default.
- W1990207169 hasConceptScore W1990207169C86811712 @default.
- W1990207169 hasConceptScore W1990207169C98274493 @default.
- W1990207169 hasFunder F4320320912 @default.
- W1990207169 hasIssue "4" @default.
- W1990207169 hasLocation W19902071691 @default.
- W1990207169 hasLocation W19902071692 @default.
- W1990207169 hasOpenAccess W1990207169 @default.
- W1990207169 hasPrimaryLocation W19902071691 @default.
- W1990207169 hasRelatedWork W1990207169 @default.
- W1990207169 hasRelatedWork W2012772291 @default.
- W1990207169 hasRelatedWork W2027188071 @default.
- W1990207169 hasRelatedWork W2079910640 @default.
- W1990207169 hasRelatedWork W2083079540 @default.
- W1990207169 hasRelatedWork W2085654923 @default.
- W1990207169 hasRelatedWork W2113485059 @default.
- W1990207169 hasRelatedWork W2135126224 @default.
- W1990207169 hasRelatedWork W2185389978 @default.
- W1990207169 hasRelatedWork W2412082494 @default.
- W1990207169 hasVolume "58" @default.
- W1990207169 isParatext "false" @default.
- W1990207169 isRetracted "false" @default.
- W1990207169 magId "1990207169" @default.
- W1990207169 workType "article" @default.