Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990235799> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1990235799 endingPage "161" @default.
- W1990235799 startingPage "161" @default.
- W1990235799 abstract "Introduction: Limbic encephalitis (LE) is characterized by rapidly progressive short-term memory loss, psychiatric symptoms and seizures. We describe the clinical spectrum, underlying etiology and long-term follow-up of patients with LE from India. Materials and Methods: This prospective study included patients during the period of January 2009 and December 2011 with the clinical features consistent with LE with one or more of the following: (1) Magnetic resonance imaging (MRI) evidence of temporal lobe involvement; (2) cerebrospinal fluid inflammatory abnormalities, or (3) detection of antineuronal antibodies. Patients with metastasis, infection, metabolic and nutritional deficits, stroke, were excluded. Results: There were 16 patients (9 females), mean age of presentation was 36.6 years (range 15-69 years). The mean duration of symptoms before presentation was 11 months (range 5 days-2 years). The most common symptom at presentation was short-term memory impairment in 7 patients followed by seizures in 5 and behavioral changes in three. Nine patients had seizures, 11 had change in behavior, language involvement in eight, cerebellar features in 3 and autonomic dysfunction in two. Four patients had associated malignancy, 3 of four presented with neurological symptoms and on investigations found to be have malignancy. Antineuronal antibody testing was done in 6 of 12 non paraneoplastic and two paraneoplastic patients, one positive for N-methyl-D-aspartate and one for anti-Hu antibody. MRI brain showed typical fluid attenuated inversion recovery or T2 bilateral temporal lobe hyperintensities in 50% of patients. At a mean follow-up of 21 months (3-36 months), 10 patients improved, 4 patients remained same and two patients expired. Conclusion: Early recognition of LE is important based upon clinical, MRI data in the absence of antineuronal surface antibody screen in developing nations. Early institution of immunotherapy will help in improvement in outcome of these patients in long-term." @default.
- W1990235799 created "2016-06-24" @default.
- W1990235799 creator A5000103652 @default.
- W1990235799 creator A5004570601 @default.
- W1990235799 creator A5026016121 @default.
- W1990235799 creator A5052151446 @default.
- W1990235799 creator A5065271543 @default.
- W1990235799 date "2014-01-01" @default.
- W1990235799 modified "2023-09-27" @default.
- W1990235799 title "Limbic encephalitis: Clinical spectrum and long-term outcome from a developing country perspective" @default.
- W1990235799 doi "https://doi.org/10.4103/0972-2327.132615" @default.
- W1990235799 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4090840" @default.
- W1990235799 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25024565" @default.
- W1990235799 hasPublicationYear "2014" @default.
- W1990235799 type Work @default.
- W1990235799 sameAs 1990235799 @default.
- W1990235799 citedByCount "11" @default.
- W1990235799 countsByYear W19902357992016 @default.
- W1990235799 countsByYear W19902357992018 @default.
- W1990235799 countsByYear W19902357992020 @default.
- W1990235799 countsByYear W19902357992022 @default.
- W1990235799 countsByYear W19902357992023 @default.
- W1990235799 crossrefType "journal-article" @default.
- W1990235799 hasAuthorship W1990235799A5000103652 @default.
- W1990235799 hasAuthorship W1990235799A5004570601 @default.
- W1990235799 hasAuthorship W1990235799A5026016121 @default.
- W1990235799 hasAuthorship W1990235799A5052151446 @default.
- W1990235799 hasAuthorship W1990235799A5065271543 @default.
- W1990235799 hasBestOaLocation W19902357991 @default.
- W1990235799 hasConcept C118552586 @default.
- W1990235799 hasConcept C126322002 @default.
- W1990235799 hasConcept C126838900 @default.
- W1990235799 hasConcept C137627325 @default.
- W1990235799 hasConcept C142724271 @default.
- W1990235799 hasConcept C143409427 @default.
- W1990235799 hasConcept C146638467 @default.
- W1990235799 hasConcept C187212893 @default.
- W1990235799 hasConcept C203014093 @default.
- W1990235799 hasConcept C2522874641 @default.
- W1990235799 hasConcept C2777699746 @default.
- W1990235799 hasConcept C2778186239 @default.
- W1990235799 hasConcept C2779399171 @default.
- W1990235799 hasConcept C2781099131 @default.
- W1990235799 hasConcept C71924100 @default.
- W1990235799 hasConcept C83455156 @default.
- W1990235799 hasConceptScore W1990235799C118552586 @default.
- W1990235799 hasConceptScore W1990235799C126322002 @default.
- W1990235799 hasConceptScore W1990235799C126838900 @default.
- W1990235799 hasConceptScore W1990235799C137627325 @default.
- W1990235799 hasConceptScore W1990235799C142724271 @default.
- W1990235799 hasConceptScore W1990235799C143409427 @default.
- W1990235799 hasConceptScore W1990235799C146638467 @default.
- W1990235799 hasConceptScore W1990235799C187212893 @default.
- W1990235799 hasConceptScore W1990235799C203014093 @default.
- W1990235799 hasConceptScore W1990235799C2522874641 @default.
- W1990235799 hasConceptScore W1990235799C2777699746 @default.
- W1990235799 hasConceptScore W1990235799C2778186239 @default.
- W1990235799 hasConceptScore W1990235799C2779399171 @default.
- W1990235799 hasConceptScore W1990235799C2781099131 @default.
- W1990235799 hasConceptScore W1990235799C71924100 @default.
- W1990235799 hasConceptScore W1990235799C83455156 @default.
- W1990235799 hasIssue "2" @default.
- W1990235799 hasLocation W19902357991 @default.
- W1990235799 hasLocation W19902357992 @default.
- W1990235799 hasLocation W19902357993 @default.
- W1990235799 hasLocation W19902357994 @default.
- W1990235799 hasOpenAccess W1990235799 @default.
- W1990235799 hasPrimaryLocation W19902357991 @default.
- W1990235799 hasRelatedWork W2013957148 @default.
- W1990235799 hasRelatedWork W2033003825 @default.
- W1990235799 hasRelatedWork W2056104786 @default.
- W1990235799 hasRelatedWork W2312654430 @default.
- W1990235799 hasRelatedWork W2411853811 @default.
- W1990235799 hasRelatedWork W2895640149 @default.
- W1990235799 hasRelatedWork W3117399034 @default.
- W1990235799 hasRelatedWork W4210833783 @default.
- W1990235799 hasRelatedWork W4224273780 @default.
- W1990235799 hasRelatedWork W4312430862 @default.
- W1990235799 hasVolume "17" @default.
- W1990235799 isParatext "false" @default.
- W1990235799 isRetracted "false" @default.
- W1990235799 magId "1990235799" @default.
- W1990235799 workType "article" @default.