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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990257247> ?p ?o ?g. }

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• W1990257247 abstract "The analgesic buprenorphine hydrochloride (Bph) induced apoptosis-like cell death in the caspase-3-deficient human breast cancer cell line, MCF-7. This apoptosis-like cell death activated key molecules in the mitochondrial apoptotic pathway: cytochrome c, caspase-9, caspase-7, and caspase-6. Bph caused the release of fluorescent protein from the mitochondria of MCF-7 cells transfected with the pDsRed2-Mito®-vector in a time-dependent manner, suggesting disruption of the mitochondrial membrane. Zn2+ as high as 2 mM did not inhibit the DNase that took part in this apoptosis. Thus, this unidentified DNase might resemble other DNases involved in apoptosis-like cell death whose activity is not inhibited by zinc ion." @default.
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• W1990257247 date "2004-06-01" @default.
• W1990257247 modified "2023-09-26" @default.
• W1990257247 title "Apoptosis-like cell death of human breast cancer cell line MCF-7 induced by buprenorphine hydrochloride" @default.
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• W1990257247 doi "https://doi.org/10.1016/j.lfs.2003.11.032" @default.
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