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- W1990260981 abstract "Nectins and nectin-like molecules (Necls) are immunoglobulin-like cell adhesion molecules that constitute families containing four and five members, respectively. All members, except for Necl-5, trans-interact homophilically. Furthermore, all members, including Necl-5, trans-interact heterophilically with their respective specific partners among the members. Necl-5 regulates cell movement and proliferation cooperatively with integrin alphavbeta3 and growth factor receptors. Nectins function as cell-cell adhesion molecules at a variety of cell-cell junctions, including adherens junctions, and regulate the initial step of cell-cell junction formation. Nectins and integrin alphavbeta3 are further involved in the cross-talk between cell-matrix and cell-cell junctions. Thus, both nectin and Necl family members play important roles in fundamental cellular functions, including cell adhesion, polarization, movement, and proliferation." @default.
- W1990260981 created "2016-06-24" @default.
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- W1990260981 date "2006-05-01" @default.
- W1990260981 modified "2023-10-17" @default.
- W1990260981 title "Nectins and nectin‐like molecules: Roles in cell adhesion, polarization, movement, and proliferation" @default.
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- W1990260981 doi "https://doi.org/10.1080/15216540600719622" @default.
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