FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990280589> ?p ?o ?g. }

• W1990280589 endingPage "626" @default.
• W1990280589 startingPage "618" @default.
• W1990280589 abstract "Cytogenetic findings of our 30 previously reported and eight new patients with malignant pleural mesothelioma were summarised and correlated with asbestos fibre burden in lung tissue and survival. Successful cytogenetic analyses were performed on cells obtained from the tumours and/or pleural effusions of 34 of the 38 patients. Clonal chromosomal abnormalities were detected in 25 patients, 19 of them studied before treatment. Nine patients, seven of them studied before treatment, had normal karyotypes and/or non-clonal chromosomal abnormalities. Most of the karyotypic findings in the patients with clonal abnormalities were complex and heterogeneous, and no chromosome aberration specific to mesothelioma could be demonstrated. The following numerical abnormalities in decreasing order of frequency were preferentially present in karyotypic changes: -22, +7, -1, -3, -9, +11 and -14 (-/+ denoting partial or total loss or gain). Translocations and deletions involving a breakpoint at 1p11-p22 were the most frequent structural aberrations. Statistically significant correlations were found between high content of asbestos fibres in lung tissue and partial or total losses of chromosomes 1 and 4, and a breakpoint at 1p11-p22 (P = 0.0001, P = 0.003, P = 0.009, respectively). The number of copies of chromosome 7 short arms was inversely correlated with survival (P = 0.02). In this study no diagnostic cytogenetic markers of mesothelioma were found, instead the copy number of chromosome 7 short arms turned out to be a possible prognostic factor in malignant mesothelioma." @default.
• W1990280589 created "2016-06-24" @default.
• W1990280589 creator A5019040135 @default.
• W1990280589 creator A5034158111 @default.
• W1990280589 creator A5036185134 @default.
• W1990280589 creator A5044523017 @default.
• W1990280589 creator A5047063635 @default.
• W1990280589 creator A5090693560 @default.
• W1990280589 date "1989-10-01" @default.
• W1990280589 modified "2023-10-07" @default.
• W1990280589 title "Chromosomal abnormalities and their correlations with asbestos exposure and survival in patients with mesothelioma" @default.
• W1990280589 cites W148347120 @default.
• W1990280589 cites W1491421164 @default.
• W1990280589 cites W1493093904 @default.
• W1990280589 cites W1602193081 @default.
• W1990280589 cites W1618234550 @default.
• W1990280589 cites W1980049624 @default.
• W1990280589 cites W1985492782 @default.
• W1990280589 cites W2008468198 @default.
• W1990280589 cites W2010965145 @default.
• W1990280589 cites W2013921702 @default.
• W1990280589 cites W2014068586 @default.
• W1990280589 cites W2015607826 @default.
• W1990280589 cites W2026158187 @default.
• W1990280589 cites W2026176404 @default.
• W1990280589 cites W2028193011 @default.
• W1990280589 cites W2052693644 @default.
• W1990280589 cites W2063400749 @default.
• W1990280589 cites W2069349857 @default.
• W1990280589 cites W2081837269 @default.
• W1990280589 cites W2087769076 @default.
• W1990280589 cites W2088245458 @default.
• W1990280589 cites W2092065359 @default.
• W1990280589 cites W2127686682 @default.
• W1990280589 cites W2143444317 @default.
• W1990280589 cites W2161381655 @default.
• W1990280589 cites W2163713766 @default.
• W1990280589 cites W2280916745 @default.
• W1990280589 cites W2401999798 @default.
• W1990280589 cites W2415362244 @default.
• W1990280589 cites W2424765761 @default.
• W1990280589 cites W259776530 @default.
• W1990280589 cites W4290441073 @default.
• W1990280589 doi "https://doi.org/10.1038/bjc.1989.326" @default.
• W1990280589 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2247120" @default.
• W1990280589 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2803935" @default.
• W1990280589 hasPublicationYear "1989" @default.
• W1990280589 type Work @default.
• W1990280589 sameAs 1990280589 @default.
• W1990280589 citedByCount "93" @default.
• W1990280589 countsByYear W19902805892012 @default.
• W1990280589 countsByYear W19902805892013 @default.
• W1990280589 countsByYear W19902805892014 @default.
• W1990280589 countsByYear W19902805892015 @default.
• W1990280589 countsByYear W19902805892016 @default.
• W1990280589 countsByYear W19902805892017 @default.
• W1990280589 countsByYear W19902805892019 @default.
• W1990280589 countsByYear W19902805892021 @default.
• W1990280589 countsByYear W19902805892022 @default.
• W1990280589 crossrefType "journal-article" @default.
• W1990280589 hasAuthorship W1990280589A5019040135 @default.
• W1990280589 hasAuthorship W1990280589A5034158111 @default.
• W1990280589 hasAuthorship W1990280589A5036185134 @default.
• W1990280589 hasAuthorship W1990280589A5044523017 @default.
• W1990280589 hasAuthorship W1990280589A5047063635 @default.
• W1990280589 hasAuthorship W1990280589A5090693560 @default.
• W1990280589 hasBestOaLocation W19902805891 @default.
• W1990280589 hasConcept C104317684 @default.
• W1990280589 hasConcept C126322002 @default.
• W1990280589 hasConcept C138626823 @default.
• W1990280589 hasConcept C142724271 @default.
• W1990280589 hasConcept C174475383 @default.
• W1990280589 hasConcept C191897082 @default.
• W1990280589 hasConcept C192562407 @default.
• W1990280589 hasConcept C206936463 @default.
• W1990280589 hasConcept C2776178081 @default.
• W1990280589 hasConcept C2776517811 @default.
• W1990280589 hasConcept C2777407522 @default.
• W1990280589 hasConcept C2777714996 @default.
• W1990280589 hasConcept C2779672484 @default.
• W1990280589 hasConcept C30481170 @default.
• W1990280589 hasConcept C510490043 @default.
• W1990280589 hasConcept C53226629 @default.
• W1990280589 hasConcept C54355233 @default.
• W1990280589 hasConcept C71924100 @default.
• W1990280589 hasConcept C86803240 @default.
• W1990280589 hasConceptScore W1990280589C104317684 @default.
• W1990280589 hasConceptScore W1990280589C126322002 @default.
• W1990280589 hasConceptScore W1990280589C138626823 @default.
• W1990280589 hasConceptScore W1990280589C142724271 @default.
• W1990280589 hasConceptScore W1990280589C174475383 @default.
• W1990280589 hasConceptScore W1990280589C191897082 @default.
• W1990280589 hasConceptScore W1990280589C192562407 @default.
• W1990280589 hasConceptScore W1990280589C206936463 @default.
• W1990280589 hasConceptScore W1990280589C2776178081 @default.
• W1990280589 hasConceptScore W1990280589C2776517811 @default.
• W1990280589 hasConceptScore W1990280589C2777407522 @default.
• W1990280589 hasConceptScore W1990280589C2777714996 @default.

• next