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• W1990283675 abstract "Metabolic changes in rabbit cornea after combined long-term steroid treatment and UV-B exposure were investigated. Corneas were exposed to UV-B radiation (2.05 J/cm2) after 36 days topical pretreatment with either 0.1% dexamethasone or saline. Twenty-four hours after UV-B exposure, corneas were excised and aqueous humour aspirated. Intact corneal tissues were analyzed by magic angle spinning proton NMR spectroscopy and pattern recognition methods. UV-B decreased corneal ascorbate (63% reduction), taurine (62%), and choline (63%), whereas glucose was elevated. Dexamethasone pretreatment further depleted corneal taurine and ascorbate, decreased aqueous ascorbate (85%), and accumulated glucose in cornea and aqueous humour. The results reflect antioxidative mechanisms and osmoregulation." @default.
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• W1990283675 date "2005-01-01" @default.
• W1990283675 modified "2023-10-16" @default.
• W1990283675 title "High-Resolution MAS¹H NMR Spectroscopic Analysis of Rabbit Cornea After Treatment with Dexamethasone and Exposure to UV-B Radiation" @default.
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• W1990283675 doi "https://doi.org/10.1080/02713680500320737" @default.
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