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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990298910> ?p ?o ?g. }

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• W1990298910 abstract "Previously, we identified an 80 kDa membrane protein (LMP80) that is capable of binding to LPS and lipid A in the presence of LBP and sCD14. LMP80 could also be detected after immuno-coprecipitation of cell membranes with LPS and lipid A, indicating a physical contact of LMP80 and LPS/lipid A. Further analysis and peptide sequencing revealed that LMP80 is identical to CD55 (decay accelerating factor, DAF), a regulatory molecule of the complement cascade. Transfection of LPS-hyporesponsive Chinese hamster ovary (CHO) cells with human CD55 resulted in the translocation of NF-κB upon stimulation with LPS or lipid A. Our results demonstrate a new functional role of CD55 as a molecule able to mediate LPS-induced activation of cells that may be part of a multimeric LPS receptor complex." @default.
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• W1990298910 date "2001-06-01" @default.
• W1990298910 modified "2023-09-27" @default.
• W1990298910 title "Decay-accelerating factor (DAF/CD55) is a functional active element of the LPS receptor complex" @default.
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• W1990298910 doi "https://doi.org/10.1177/09680519010070030601" @default.
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