FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990333432> ?p ?o ?g. }

• W1990333432 endingPage "980" @default.
• W1990333432 startingPage "973" @default.
• W1990333432 abstract "The aim of this study is to explore beta cell dysfunction and its clinical significance in gestational diabetes mellitus (GDM). We assessed insulin sensitivity and insulin secretion in a total of 277 Japanese women between 24 and 27 weeks of pregnancy who underwent a 2 h, 75 g oral glucose tolerance test (OGTT) because of an abnormal result on a 1 h 50 g oral glucose challenge conducted as part of a standard screening for GDM. Insulin sensitivity was evaluated by an insulin sensitivity index derived from OGTT (ISOGTT), whereas insulin secretion was calculated as a ratio of the total area under the insulin curve to the total area under the glucose curve (AUCins/glu). Beta cell function in relation to insulin sensitivity (i.e. disposition index) was derived from the product of insulin sensitivity and insulin secretion (i.e. AUCins/glu × ISOGTT). In women diagnosed with GDM (n=57), the disposition index was significantly lower than that in those without GDM, irrespective of obesity. The disposition index in women with GDM was significantly correlated with levels of fasting and mean preprandial capillary glucose and HbA1c before initiating insulin therapy (r = -0.45, -0.38, -0.49, respectively). Furthermore, there was a significant correlation between the disposition index and total insulin dosage to achieve glycemic goal (r = -0.41). In conclusion, we demonstrated beta cell dysfunction in Japanese women with GDM irrespective of obesity. The level of beta cell dysfunction in GDM was associated with the severity of glucose intolerance and total insulin dosage required. These findings underpin clinical significance of beta cell dysfunction in GDM." @default.
• W1990333432 created "2016-06-24" @default.
• W1990333432 creator A5004867359 @default.
• W1990333432 creator A5013836607 @default.
• W1990333432 creator A5048351946 @default.
• W1990333432 creator A5057556279 @default.
• W1990333432 creator A5059378687 @default.
• W1990333432 creator A5077665206 @default.
• W1990333432 creator A5082558983 @default.
• W1990333432 creator A5086401815 @default.
• W1990333432 date "2010-01-01" @default.
• W1990333432 modified "2023-10-03" @default.
• W1990333432 title "Beta cell dysfunction and its clinical significance in gestational diabetes" @default.
• W1990333432 cites W1917798655 @default.
• W1990333432 cites W1917860558 @default.
• W1990333432 cites W1972861341 @default.
• W1990333432 cites W1982307662 @default.
• W1990333432 cites W1988760852 @default.
• W1990333432 cites W2006126067 @default.
• W1990333432 cites W2023300718 @default.
• W1990333432 cites W2043329700 @default.
• W1990333432 cites W2076450470 @default.
• W1990333432 cites W2080939423 @default.
• W1990333432 cites W2088724567 @default.
• W1990333432 cites W2126878764 @default.
• W1990333432 cites W2133795831 @default.
• W1990333432 cites W2169464389 @default.
• W1990333432 cites W4233477876 @default.
• W1990333432 cites W4235374500 @default.
• W1990333432 doi "https://doi.org/10.1507/endocrj.k10e-231" @default.
• W1990333432 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20847480" @default.
• W1990333432 hasPublicationYear "2010" @default.
• W1990333432 type Work @default.
• W1990333432 sameAs 1990333432 @default.
• W1990333432 citedByCount "50" @default.
• W1990333432 countsByYear W19903334322012 @default.
• W1990333432 countsByYear W19903334322013 @default.
• W1990333432 countsByYear W19903334322014 @default.
• W1990333432 countsByYear W19903334322015 @default.
• W1990333432 countsByYear W19903334322016 @default.
• W1990333432 countsByYear W19903334322017 @default.
• W1990333432 countsByYear W19903334322018 @default.
• W1990333432 countsByYear W19903334322019 @default.
• W1990333432 countsByYear W19903334322020 @default.
• W1990333432 countsByYear W19903334322021 @default.
• W1990333432 countsByYear W19903334322022 @default.
• W1990333432 countsByYear W19903334322023 @default.
• W1990333432 crossrefType "journal-article" @default.
• W1990333432 hasAuthorship W1990333432A5004867359 @default.
• W1990333432 hasAuthorship W1990333432A5013836607 @default.
• W1990333432 hasAuthorship W1990333432A5048351946 @default.
• W1990333432 hasAuthorship W1990333432A5057556279 @default.
• W1990333432 hasAuthorship W1990333432A5059378687 @default.
• W1990333432 hasAuthorship W1990333432A5077665206 @default.
• W1990333432 hasAuthorship W1990333432A5082558983 @default.
• W1990333432 hasAuthorship W1990333432A5086401815 @default.
• W1990333432 hasBestOaLocation W19903334321 @default.
• W1990333432 hasConcept C126322002 @default.
• W1990333432 hasConcept C134018914 @default.
• W1990333432 hasConcept C15744967 @default.
• W1990333432 hasConcept C2776652674 @default.
• W1990333432 hasConcept C2779234561 @default.
• W1990333432 hasConcept C2779306644 @default.
• W1990333432 hasConcept C2779434492 @default.
• W1990333432 hasConcept C2780221984 @default.
• W1990333432 hasConcept C2780473172 @default.
• W1990333432 hasConcept C38022665 @default.
• W1990333432 hasConcept C46973012 @default.
• W1990333432 hasConcept C54355233 @default.
• W1990333432 hasConcept C555293320 @default.
• W1990333432 hasConcept C71924100 @default.
• W1990333432 hasConcept C77805123 @default.
• W1990333432 hasConcept C86803240 @default.
• W1990333432 hasConceptScore W1990333432C126322002 @default.
• W1990333432 hasConceptScore W1990333432C134018914 @default.
• W1990333432 hasConceptScore W1990333432C15744967 @default.
• W1990333432 hasConceptScore W1990333432C2776652674 @default.
• W1990333432 hasConceptScore W1990333432C2779234561 @default.
• W1990333432 hasConceptScore W1990333432C2779306644 @default.
• W1990333432 hasConceptScore W1990333432C2779434492 @default.
• W1990333432 hasConceptScore W1990333432C2780221984 @default.
• W1990333432 hasConceptScore W1990333432C2780473172 @default.
• W1990333432 hasConceptScore W1990333432C38022665 @default.
• W1990333432 hasConceptScore W1990333432C46973012 @default.
• W1990333432 hasConceptScore W1990333432C54355233 @default.
• W1990333432 hasConceptScore W1990333432C555293320 @default.
• W1990333432 hasConceptScore W1990333432C71924100 @default.
• W1990333432 hasConceptScore W1990333432C77805123 @default.
• W1990333432 hasConceptScore W1990333432C86803240 @default.
• W1990333432 hasIssue "11" @default.
• W1990333432 hasLocation W19903334321 @default.
• W1990333432 hasLocation W19903334322 @default.
• W1990333432 hasOpenAccess W1990333432 @default.
• W1990333432 hasPrimaryLocation W19903334321 @default.
• W1990333432 hasRelatedWork W1983641721 @default.
• W1990333432 hasRelatedWork W1995945960 @default.
• W1990333432 hasRelatedWork W2026226896 @default.
• W1990333432 hasRelatedWork W2032033851 @default.

• next