FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990334057> ?p ?o ?g. }

• W1990334057 endingPage "198" @default.
• W1990334057 startingPage "198" @default.
• W1990334057 abstract "Purpose: To fast and accurately compute the actual dose delivered to the patient during the intensity-modulated radiotherapy (IMRT) for treatment quality assessment and adaptive radiotherapy. Methods: A fast deformable image registration (DIR) and dose computation engines both accelerated by a graphics processing unit (GPU) are implemented and integrated into a unified framework. DIR automatically aligns the planning CT (pCT) to daily cone-beam CTs (CBCTs) by a rigid registration followed by a b-spline registration using mutual information as a similarity metric. The dose engine computes the dose on the registered pCT by using a superposition/convolution technique. The implemented tool was tested on a retrospective image data set of a head and neck cancer patient. The pCT was registered to 13 CBCTs (among 30 fractions) and the actual dose was computed on each registered CT. Results: The average computation time for DIR of the pCT and CBCT of 512×512×136 was less than one minute. The dose was computed on a 171×171×136 grid with the grid size of 3.8×3.8×3.0 mm3, and the average computation time was 0.6 second/beam. The registered pCT showed 7.5% improvement in terms of normalized cross-correlation with the CBCT while simple couch shifts showed only 4.4% improvement. Our GPU dose engine enables over 30 times speed-up over the highly optimized commercial treatment planning software (Pinnacle, Philips, Madison, WI). Conclusion: A unified framework for computing the actual dose delivered to the patient was implemented. The implemented tool significantly improves the accuracy of dose computation by DIR followed by direct dose computation on the deformed pCT while maintaining a substantially improved performance over CPU-based implementations. The superior performance of this tool will enable an efficient and accurate on-line dose computation for treatment quality assessment and adaptive radiotherapy. This work was supported in part by National Science Foundation under grant No. EEC9731748, in part by Johns Hopkins University internal funds, and in part by National Institute of Health - National Cancer Institute under grant No. 2R42CA137886." @default.
• W1990334057 created "2016-06-24" @default.
• W1990334057 creator A5011806472 @default.
• W1990334057 creator A5013489602 @default.
• W1990334057 creator A5015444670 @default.
• W1990334057 creator A5021359286 @default.
• W1990334057 creator A5060997298 @default.
• W1990334057 creator A5063669795 @default.
• W1990334057 creator A5064131953 @default.
• W1990334057 creator A5089858828 @default.
• W1990334057 date "2013-06-01" @default.
• W1990334057 modified "2023-10-16" @default.
• W1990334057 title "SU-E-J-205: Fast Computation of Actual Dose Delivered to the Patient for IMRT Treatment Quality Assessment and Adaptive Radiotherapy" @default.
• W1990334057 doi "https://doi.org/10.1118/1.4814417" @default.
• W1990334057 hasPublicationYear "2013" @default.
• W1990334057 type Work @default.
• W1990334057 sameAs 1990334057 @default.
• W1990334057 citedByCount "0" @default.
• W1990334057 crossrefType "journal-article" @default.
• W1990334057 hasAuthorship W1990334057A5011806472 @default.
• W1990334057 hasAuthorship W1990334057A5013489602 @default.
• W1990334057 hasAuthorship W1990334057A5015444670 @default.
• W1990334057 hasAuthorship W1990334057A5021359286 @default.
• W1990334057 hasAuthorship W1990334057A5060997298 @default.
• W1990334057 hasAuthorship W1990334057A5063669795 @default.
• W1990334057 hasAuthorship W1990334057A5064131953 @default.
• W1990334057 hasAuthorship W1990334057A5089858828 @default.
• W1990334057 hasConcept C11413529 @default.
• W1990334057 hasConcept C115961682 @default.
• W1990334057 hasConcept C126838900 @default.
• W1990334057 hasConcept C154945302 @default.
• W1990334057 hasConcept C166704113 @default.
• W1990334057 hasConcept C201645570 @default.
• W1990334057 hasConcept C2779813781 @default.
• W1990334057 hasConcept C2989005 @default.
• W1990334057 hasConcept C31601959 @default.
• W1990334057 hasConcept C41008148 @default.
• W1990334057 hasConcept C45374587 @default.
• W1990334057 hasConcept C509974204 @default.
• W1990334057 hasConcept C544519230 @default.
• W1990334057 hasConcept C55020928 @default.
• W1990334057 hasConcept C71924100 @default.
• W1990334057 hasConcept C75088862 @default.
• W1990334057 hasConcept C9267231 @default.
• W1990334057 hasConceptScore W1990334057C11413529 @default.
• W1990334057 hasConceptScore W1990334057C115961682 @default.
• W1990334057 hasConceptScore W1990334057C126838900 @default.
• W1990334057 hasConceptScore W1990334057C154945302 @default.
• W1990334057 hasConceptScore W1990334057C166704113 @default.
• W1990334057 hasConceptScore W1990334057C201645570 @default.
• W1990334057 hasConceptScore W1990334057C2779813781 @default.
• W1990334057 hasConceptScore W1990334057C2989005 @default.
• W1990334057 hasConceptScore W1990334057C31601959 @default.
• W1990334057 hasConceptScore W1990334057C41008148 @default.
• W1990334057 hasConceptScore W1990334057C45374587 @default.
• W1990334057 hasConceptScore W1990334057C509974204 @default.
• W1990334057 hasConceptScore W1990334057C544519230 @default.
• W1990334057 hasConceptScore W1990334057C55020928 @default.
• W1990334057 hasConceptScore W1990334057C71924100 @default.
• W1990334057 hasConceptScore W1990334057C75088862 @default.
• W1990334057 hasConceptScore W1990334057C9267231 @default.
• W1990334057 hasIssue "6Part10" @default.
• W1990334057 hasLocation W19903340571 @default.
• W1990334057 hasOpenAccess W1990334057 @default.
• W1990334057 hasPrimaryLocation W19903340571 @default.
• W1990334057 hasRelatedWork W1992591491 @default.
• W1990334057 hasRelatedWork W2025656351 @default.
• W1990334057 hasRelatedWork W2029646342 @default.
• W1990334057 hasRelatedWork W2033661381 @default.
• W1990334057 hasRelatedWork W2044950871 @default.
• W1990334057 hasRelatedWork W2070741266 @default.
• W1990334057 hasRelatedWork W2897755262 @default.
• W1990334057 hasRelatedWork W2944277128 @default.
• W1990334057 hasRelatedWork W3005262506 @default.
• W1990334057 hasRelatedWork W957382563 @default.
• W1990334057 hasVolume "40" @default.
• W1990334057 isParatext "false" @default.
• W1990334057 isRetracted "false" @default.
• W1990334057 magId "1990334057" @default.
• W1990334057 workType "article" @default.