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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990337002> ?p ?o ?g. }

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• W1990337002 abstract "We synthesized and evaluated by surface plasmon resonance 64 LNA/2′‐ O ‐methyl sequences corresponding to all possible combinations of such residues in a kissing aptamer loop complementary to the 6‐nt loop of the TAR element of HIV‐1. Three combinations of LNA/2′‐ O ‐methyl nucleoside analogues where one or two LNA units are located on the 3′ side of the aptamer loop display an affinity for TAR below 1 nM, i.e. one order of magnitude higher than the parent RNA aptamer. One of these combinations inhibits the TAR‐dependent luciferase expression in a cell assay." @default.
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• W1990337002 date "2007-01-30" @default.
• W1990337002 modified "2023-10-13" @default.
• W1990337002 title "Systematic screening of LNA/2′-<i>O</i>-methyl chimeric derivatives of a TAR RNA aptamer" @default.
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• W1990337002 doi "https://doi.org/10.1016/j.febslet.2007.01.047" @default.
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