FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1990339744> ?p ?o ?g. }

• W1990339744 endingPage "811" @default.
• W1990339744 startingPage "800" @default.
• W1990339744 abstract "Scale-up from shake flasks to fermenters has been hampered by the lack of knowledge concerning the influence of operating conditions on mass transfer, hydromechanics, and power input. However, in recent years the properties of shake flasks have been described with empirical models. A practical scale-up strategy for everyday use is introduced for the scale-up of aerobic cultures from shake flasks to fermenters in batch and continuous mode. The strategy is based on empirical correlations of the volumetric mass transfer coefficient (kL a) and the pH. The accuracy of the empirical kL a correlations and the assumptions required to use these correlations for an arbitrary biological medium are discussed. To determine the optimal pH of the culture medium a simple laboratory method based on titration curves of the medium and a mechanistic pH model, which is solely based on the medium composition, is applied. The effectiveness of the scale-up strategy is demonstrated by comparing the behavior of Corynebacterium glutamicum on lactic acid in shake flasks and fermenters in batch and continuous mode. The maximum growth rate (µmax = 0.32 h−1) and the oxygen substrate coefficient ( = 0.0174 mol/l) of C. glutamicum on lactic acid were equal for shake flask, fermenter, batch, and continuous cultures. The biomass substrate yield was independent of the scale, but was lower in batch cultures (YX/S = 0.36 g/g) than in continuous cultures (YX/S = 0.45 g/g). The experimental data (biomass, respiration, pH) could be described with a simple biological model combined with a mechanistic pH model. Biotechnol. Bioeng. 2007; 98: 800–811. © 2007 Wiley Periodicals, Inc." @default.
• W1990339744 created "2016-06-24" @default.
• W1990339744 creator A5013041284 @default.
• W1990339744 creator A5020297199 @default.
• W1990339744 creator A5022603631 @default.
• W1990339744 creator A5027383616 @default.
• W1990339744 creator A5041676417 @default.
• W1990339744 creator A5046286469 @default.
• W1990339744 creator A5089032733 @default.
• W1990339744 date "2007-01-01" @default.
• W1990339744 modified "2023-10-03" @default.
• W1990339744 title "Scale-up from shake flasks to fermenters in batch and continuous mode withCorynebacterium glutamicum on lactic acid based on oxygen transfer and pH" @default.
• W1990339744 cites W1554160295 @default.
• W1990339744 cites W1965876945 @default.
• W1990339744 cites W1969943795 @default.
• W1990339744 cites W1973602979 @default.
• W1990339744 cites W1974027159 @default.
• W1990339744 cites W1978439824 @default.
• W1990339744 cites W1978713386 @default.
• W1990339744 cites W1981203871 @default.
• W1990339744 cites W1983780141 @default.
• W1990339744 cites W1987167366 @default.
• W1990339744 cites W1987189516 @default.
• W1990339744 cites W1991611436 @default.
• W1990339744 cites W1994774138 @default.
• W1990339744 cites W1994960467 @default.
• W1990339744 cites W1998765941 @default.
• W1990339744 cites W2012495769 @default.
• W1990339744 cites W2015856455 @default.
• W1990339744 cites W2016812228 @default.
• W1990339744 cites W2019794366 @default.
• W1990339744 cites W2024898389 @default.
• W1990339744 cites W2037910915 @default.
• W1990339744 cites W2038862697 @default.
• W1990339744 cites W2038936694 @default.
• W1990339744 cites W2044013498 @default.
• W1990339744 cites W2044828094 @default.
• W1990339744 cites W2045439749 @default.
• W1990339744 cites W2046947265 @default.
• W1990339744 cites W2047705017 @default.
• W1990339744 cites W2063883386 @default.
• W1990339744 cites W2063885009 @default.
• W1990339744 cites W2064296729 @default.
• W1990339744 cites W2073134373 @default.
• W1990339744 cites W2081544371 @default.
• W1990339744 cites W2083450849 @default.
• W1990339744 cites W2092139615 @default.
• W1990339744 cites W2095998779 @default.
• W1990339744 cites W2096792209 @default.
• W1990339744 cites W2105637055 @default.
• W1990339744 cites W2122152742 @default.
• W1990339744 cites W2133221257 @default.
• W1990339744 cites W2146402498 @default.
• W1990339744 cites W2154438767 @default.
• W1990339744 cites W2162779664 @default.
• W1990339744 cites W4234083097 @default.
• W1990339744 doi "https://doi.org/10.1002/bit.21359" @default.
• W1990339744 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17318907" @default.
• W1990339744 hasPublicationYear "2007" @default.
• W1990339744 type Work @default.
• W1990339744 sameAs 1990339744 @default.
• W1990339744 citedByCount "78" @default.
• W1990339744 countsByYear W19903397442012 @default.
• W1990339744 countsByYear W19903397442013 @default.
• W1990339744 countsByYear W19903397442014 @default.
• W1990339744 countsByYear W19903397442015 @default.
• W1990339744 countsByYear W19903397442016 @default.
• W1990339744 countsByYear W19903397442017 @default.
• W1990339744 countsByYear W19903397442018 @default.
• W1990339744 countsByYear W19903397442019 @default.
• W1990339744 countsByYear W19903397442020 @default.
• W1990339744 countsByYear W19903397442021 @default.
• W1990339744 countsByYear W19903397442022 @default.
• W1990339744 countsByYear W19903397442023 @default.
• W1990339744 crossrefType "journal-article" @default.
• W1990339744 hasAuthorship W1990339744A5013041284 @default.
• W1990339744 hasAuthorship W1990339744A5020297199 @default.
• W1990339744 hasAuthorship W1990339744A5022603631 @default.
• W1990339744 hasAuthorship W1990339744A5027383616 @default.
• W1990339744 hasAuthorship W1990339744A5041676417 @default.
• W1990339744 hasAuthorship W1990339744A5046286469 @default.
• W1990339744 hasAuthorship W1990339744A5089032733 @default.
• W1990339744 hasConcept C100544194 @default.
• W1990339744 hasConcept C104317684 @default.
• W1990339744 hasConcept C115540264 @default.
• W1990339744 hasConcept C139149728 @default.
• W1990339744 hasConcept C147789679 @default.
• W1990339744 hasConcept C161790260 @default.
• W1990339744 hasConcept C168170006 @default.
• W1990339744 hasConcept C178790620 @default.
• W1990339744 hasConcept C185592680 @default.
• W1990339744 hasConcept C186060115 @default.
• W1990339744 hasConcept C2775920511 @default.
• W1990339744 hasConcept C2776260651 @default.
• W1990339744 hasConcept C43617362 @default.
• W1990339744 hasConcept C47502133 @default.
• W1990339744 hasConcept C523546767 @default.
• W1990339744 hasConcept C54355233 @default.

• next